Letter | Published:

Purification of Uricase

Nature volume 143, page 604 (08 April 1939) | Download Citation

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Abstract

URICASE is an enzyme which catalyses the oxidation of uric acid. It was reported recently by Davidson1 that he had been able to obtain a preparation of uricase about a thousand times more active than the acetone powder of liver which was used as a starting material. Several purified preparations showed, according to him, a high and fairly constant iron content ranging from 0.15 to 0.20 per cent, which he regards as evidence in favour of the view that iron is a constituent of uricase.

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References

  1. 1.

    , NATURE, 141, 790 (1938). Biochem. J., 32, 1386 (1938).

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Affiliations

  1. Molteno Institute, University of Cambridge. March 3.

    • C. G. HOLMBERG

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DOI

https://doi.org/10.1038/143604a0

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