Letter | Published:

Fatty Acids from Yeast as Respiratory Factors

Nature volume 142, page 719 (15 October 1938) | Download Citation

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Abstract

A NUMBER of papers1 from this laboratory have reported the preparation from yeast and malt-combings of fractions which stimulate the respiration of yeast and of animal tissues, particularly of skin. A study of these fractions appears to indicate the existence of a multiplicity of respiratory factors. The fractions studied thus far have been water-soluble and thermostable. They have all contained nitrogen and phosphorus, but the fractions have been manifestly impure and it has been difficult to correlate the respiratory activity with chemical properties except to indicate that protein probably plays no part. On the other hand, it has been possible to correlate the proliferation-promoting activity of preparations from yeast with nucleic acid-like materials containing guanine, adenine, phosphorus and pen-toses, and having a maximum in ultra-violet absorption2 at 2600 A.

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References

  1. 1.

    , , and , NATURE, 139, 589 (1937). and , Studies Inst. Divi ThomÅ", 1, 137 (1937). , and , Proc. Soc. Exptl. Biol. Med., 38, 169 (1938). , , and , Studies Inst. Divi Thomce, in the Press. and , ibid., in the Press.

  2. 2.

    , , and , 10th International Congress of Chemistry, Rome, May, 1938. , , and , in the Press.

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  1. Institutum Divi Thomæ, Institute of Scientific Research, Cincinnati, Ohio. Aug. 30.

    • ELTON S. COOK
    •  & CORNELIUS W. KREKE

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https://doi.org/10.1038/142719a0

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