A Coloured Intermediate on Reduction of Vitamin B1


A VERY distinct green yellowish colour appears when vitamin B1(synthetic, I. G. Farben.), in a 0·5—1 per cent solution, is reduced with hydrosulphite in the manner described in a previous note1. The intensity of the colour is highest at the beginning, declines with the declining rate of reaction and disappears at the end. The same transient green colour is observed when the vitamin is reduced with zinc dust in normal hydrochloric acid.


  1. 1

    Lipmann, NATURE, 138, 1097 (1936).

  2. 2

    Adler, Hellström and v. Euler, Z. physiol. Chem., 242, 225 (1936).

  3. 3

    Karrer and Benz, Helv. chim. Acta, 19, 1028 (1936).

  4. 4

    Michaelis, J. Biol. Chem., 92, 211 (1931).

  5. 5

    See also Erlenmeyer, Epprecht and v. Meyenburg, Helv. chim. Acta, 31, 661 (1937).

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LIPMANN, F. A Coloured Intermediate on Reduction of Vitamin B1. Nature 140, 849 (1937). https://doi.org/10.1038/140849c0

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