Letter | Published:

Porphyrins of the I and in Series III Congenital Porphyrinuria

Naturevolume 140pages105106 (1937) | Download Citation



As the result of a detailed chemical examination carried out post mortem upon a bovine suffering from congenital porphyrinuria1, and my paper appearing in the Onderstepoort Journal of Veterinary Science (vol. 7, No. 2), I have been able to isolate porphyrins similar to those found by Fischer2 and his collaborators in the human porphyrinuric Petry, but in addition have also obtained coproporphyrin, ester m.p. 243–44°, from the blood plasma and of m.p. 241° from the washed erythrocytes ; both uroporphyrin, ester m.p. 276–77°, and coproporphyrin, ester m.p. 244–45°, from the bone marrow ; uroporphyrin, ester m.p. 278°, from the spleen and uroporphyrin together with its copper complex, ester m.p. 313°, from the liver.

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  1. 1

    NATURE, 139, 68 (1937).

  2. 2

    Fischer, Hilmer, Lindner and Putzer, Z. physiol. Chem., 150, 44 (1925).

  3. 3

    Fischer and Libowitzky, Z. physiol. Chem., 241, 220 (1936).

  4. 4

    Fischer and Hofmann, Z. physiol. Chem., 246, 15 (1937).

  5. 5

    Waldenström, Deut. Archiv. klin. Med., 178, 38 (1935).

  6. 6

    Mertens, Z. physiol. Chem., 238, 1 (1936).

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  1. Onderstepoort Veterinary Research Laboratory, Pretoria, South Africa



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