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Coupled Oxidation of Ascorbic Acid and Hæmo-chromogens

Abstract

HÆMOCHROMOGENS catalyse the oxidation of ascorbic acid at a pH. below 7 at which there is no autoxidation of ascorbic acid. We can confirm this result of Barron and co-workers1, but the authors have overlooked that the hæmochromogens also undergo oxidation under these conditions, as first observed by Karrer and co-workers2. The product of this oxidation is verdohæmochromogen, a bile pigment iron compound3.

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References

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LEMBERG, R., CORTIS-JONES, B. & NORRIE, M. Coupled Oxidation of Ascorbic Acid and Hæmo-chromogens. Nature 139, 1016–1017 (1937). https://doi.org/10.1038/1391016a0

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