EXPERIMENTS on rats show that if the organism is severely damaged by acute non-specific nocuous agents such as exposure to cold, surgical injury, production of spinal shock (transcision of the cord), excessive muscular exercise, or intoxications with sublethal doses of diverse drugs (adrenaline, atropine, morphine, formaldehyde, etc.), a typical syndrome appears, the symptoms of which are independent of the nature of the damaging agent or the pharmacological type of the drug employed, and represent rather a response to damage as such.
About this article
Cite this article
SELYE, H. A Syndrome produced by Diverse Nocuous Agents. Nature 138, 32 (1936). https://doi.org/10.1038/138032a0
Adult hippocampal neurogenesis shapes adaptation and improves stress response: a mechanistic and integrative perspective
Molecular Psychiatry (2022)
Biologia Futura (2022)
Does salivary cortisol secretion mediate the association of work-related stressors with workers' depression?
International Archives of Occupational and Environmental Health (2022)
IPV Experiences and Financial Strain Over Time: Insights from the Blinder-Oaxaca Decomposition Analysis
Journal of Family and Economic Issues (2022)
Prävention und Gesundheitsförderung (2022)