Letters to Editor | Published:

Mutation Rates in Man

Naturevolume 135pages907908 (1935) | Download Citation

Subjects

Abstract

THERE is at present no information concerning mutation rates in vertebrates. But where a gene produces a very great unfitness from the Darwinian point of view, that is to say, greatly diminishes the mean number of offspring produced by its bearers, then it will tend to disappear if its numbers are not kept up by mutation. The rate of disappearance is extremely slow for an autosomal recessive, very rapid for a dominant or a sex-linked recessive.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

Author information

Affiliations

  1. Royal Eastern Counties' Institution, Colchester

    • L. S. PENROSE
  2. University College, London

    • J. B. S. HALDANE

Authors

  1. Search for L. S. PENROSE in:

  2. Search for J. B. S. HALDANE in:

About this article

Publication history

Issue Date

DOI

https://doi.org/10.1038/135907b0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.