Abstract
The three series of major chemical changes which are associated with muscular activity, namely: disintegration and resynthesis of adenosinetriphosphoric acid; disintegration and resynthesis of phosphocreatine; and glycogenolysis, or transformation of glycogen into lactic acid, have been considered, until recently, as independent chemical reactions, but as in some way linked—energetically and chemically. It was known that the presence of adenosinetriphosphoric acid is a condition of glycolysis in muscle, and that glycolysis is a condition of the resynthesis of adenosinetriphosphoric acid from adenylic acid and phosphates. Recently it has been made clear, by Lohmann1, that the resynthesis of adenosinetriphosphoric acid from adenylic acid is brought about by splitting off phosphate groups from phosphocreatine; at the same time, we have demonstrated2 the linkage between glycogenolysis and the resynthesis of adenosinetriphosphoric acid, depending probably on the intermediate resynthesis of phosphocreatine, and this later linked to a definite intermediate step of glycogenolysis.
Similar content being viewed by others
Article PDF
References
C. Lohmann, Biochem. Z., 271, 264, 278; 1934.
J. K. Parnas, P. Ostern, T. Mann, Biochem. Z., 272, 64; 1934.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
PARNAS, J., OSTERN, P. Chemistry of Anaerobic Recovery in Muscle. Nature 134, 627 (1934). https://doi.org/10.1038/134627b0
Issue Date:
DOI: https://doi.org/10.1038/134627b0
This article is cited by
-
Die Verminderung des Glykogens, des Phosphagens und der Adenylpyrophosphorsäure im Herzmuskel bei Sauerstoffmangel und nach ermüdender Arbeit normaler und trainierter Tiere
Zeitschrift fĂĽr die gesamte experimentelle Medizin (1939)
-
Die Verminderung des Glykogens, des Phosphagens und der Adenylpyrophosphorsäure im Herzmuskel bei Sauerstoffmangel und nach ermüdender Arbeit normaler und trainierter Tiere
Zeitschrift fĂĽr Die Gesamte Experimentelle Medizin (1939)
-
Über die Verkettung der Chemischen Vorgänge im Muskel
Klinische Wochenschrift (1935)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.