Abstract
FUNK1 has shown that the hormone promoting comb growth can only be extracted from the urine of men in the presence of large quantities of acid (see also Kabak2). By means of acid extraction, I demonstrated the presence of about 40 capon units per litre in hundreds of batches of normal urine, but I could not detect even 20 units per litre by injecting the fresh concentrated urine itself.
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References
Funk C., B. Harrow and A. Lejwa, Proc. Soc. Exper. Biol Med., 26, 569 ; 1929.
Kabak, J. M., Endokrinol., 9, 84, 250 ; 1931.
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ADLER, A. Active and Inactive Forms of the Hormone Promoting Comb Growth. Nature 133, 798 (1934). https://doi.org/10.1038/133798a0
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DOI: https://doi.org/10.1038/133798a0
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