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A Rapid Test for the Diagnosis of Pregnancy

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Abstract

CURRENT biological tests for the diagnosis of pregnancy or detection of ovary-stimulating substances in gland extracts and body fluids have the main disadvantage that several days must elapse before a result can be obtained. Attempts have been made to remedy this by making use of the doe rabbit, because in this animal a response (ovulation) can be obtained in less than 14 hours1. The rabbit, however, requires a good deal of care in order to obtain consistent results. It is essential to know the previous history of does employed, and preferably only to use them a short time after parturition. Even so, variation in response to injection may be so great as to necessitate the use of more than one doe in order to be sure of the result.

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Change history

  • 27 March 2018

    This article was initially published with an incorrect DOI that did not match the registered version at Crossref. The DOI has been corrected in the article.

References

  1. Bellerby, C. W., J. Physiol., 67, Proc. xxxii; 1929.

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  2. Hogben, L. T., Proc. Roy. Soc. S. Africa, March, 1930.

  3. Bellerby, C. W., Biochem. J., 27, 615, 2025; 1933.

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BELLERBY, C. A Rapid Test for the Diagnosis of Pregnancy. Nature 133, 494–495 (1934). https://doi.org/10.1038/133494b0

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