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Hat1: the emerging cellular roles of a type B histone acetyltransferase

Oncogene volume 26, pages 5319–5328 (2007)Cite this article

Abstract

Hat1 is the sole known example of a type B histone acetyltransferase. While it has long been presumed that type B histone acetyltransferases participate in the acetylation of newly synthesized histones during the process of chromatin assembly, definitive evidence linking these enzymes to this process has been scarce. This review will discuss recent results that have begun to shed light on the roles of Hat1 and also address several outstanding questions relating to the cellular function of this enzyme.

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Acknowledgements

I thank the reviewers for excellent suggestions that have improved the manuscript. Work in my laboratory related to HAT1 is supported by the National Institutes of Health (R01 GM62970).

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  1. Department of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, OH, USA

    M R Parthun

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Parthun, M. Hat1: the emerging cellular roles of a type B histone acetyltransferase. Oncogene 26, 5319–5328 (2007). https://doi.org/10.1038/sj.onc.1210602

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