Cholera: Prevention and Vaccination

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    THE epidemic of cholera with which this country is threatened seems likely to test very completely the means for the prevention of its spread which have been devised as the result of the extended experience of some of the ablest hygienists. The working out of the history of an epidemic disorder must necessarily be extended over a prolonged period of time, for it is dependent on the researches not only of the clinical observer, but of the pathologist and the bacteriologist and of those who devote themselves to the difficult study of the march of epidemics. The development of such researches is closely allied to the advance of science generally, and although there is at any one period a large admixture of “fashion” in the opinions held by experts, yet in time this fades, and the truth is established. It cannot be too clearly stated that the best measures for the prevention of an epidemic disorder can only be devised when we possess an accurate knowledge of the infective agent of the disease (bacillus or not, as the case may be), of its life-history, of its varying degrees of virulence, and the mode of entrance into the body, of the conditions under which it multiplies, and of the changes which it produces in the human body.

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    Cholera: Prevention and Vaccination. Nature 46, 466–467 (1892) doi:10.1038/046466d0

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