Nature

How India is battling deadly rain storms as climate change bites

South Asian weather is becoming increasingly difficult to forecast as monsoons grow more erratic — and global warming is raising the risks posed by violent rain storms.

COVID drug drives viral mutations — and now some want to halt its use

Analysis reveals the signature of the antiviral drug molnupiravir in SARS-CoV-2 sequences riddled with mutations.

Ewen Callaway
News 07 Feb 2023
UK government announces new science department and minister

Former universities minister Michelle Donelan is appointed head of Department for Science, Innovation and Technology in mini-reshuffle.

Brian Owens
News 07 Feb 2023
A high-mass X-ray binary descended from an ultra-stripped supernova

A recently discovered high-mass X-ray binary has an evolutionary history showing the neutron star component formed during an ultra-stripped supernova, and has orbital elements that should allow for forming a binary neutron star in the future.

Noel D. Richardson
Clarissa M. Pavao
Jeremy Hare
Article 01 Feb 2023
Daily briefing: The science underlying the Turkey–Syria earthquake

The region sits between two major faults and struggles with poor building standards in some areas. Plus, underdog technologies are gaining ground in the quantum-computing race and what ChatGPT and generative AI mean for science.

Flora Graham
Nature Briefing 07 Feb 2023
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Current Issue 09 Feb 2023

News & Comment

How to wrap up research projects gracefully

Four researchers offer tips on ending, redefining and handing over projects.

Andy Tay

Career Feature 08 Feb 2023
How India is battling deadly rain storms as climate change bites
Gayathri Vaidyanathan
News Feature 08 Feb 2023
Hidden harms of indoor air pollution — five steps to expose them
Alastair C. Lewis
Deborah Jenkins
Christopher J. M. Whitty
Comment 08 Feb 2023
Indoor air pollution kills and science needs to step up

Editorial 08 Feb 2023
An abundance of antibiotics, and more — this week’s best science graphics

News 07 Feb 2023
UK government announces new science department and minister
Brian Owens
News 07 Feb 2023
Global pandemic treaty: what we must learn from climate-change errors

Editorial 07 Feb 2023

Latest Reviews & Analysis

- Designer silicon nanowires produce hydrogen from water and light
  
  Silicon nanowires that can convert light into electricity were engineered to split water into hydrogen and oxygen. When integrated with co-catalysts and suspended in water, these light-activated nanoreactors produced hydrogen gas under visible and infrared light.
  
  Research Briefing 08 Feb 2023
- How rare mutations contribute to complex traits
  
  An analysis of rare genetic variants reveals that they influence human traits through similar biological pathways to common ones. The work deepens our understanding of how this type of variant affects complex traits.
  Luke M. Evans
  Pamela N. Romero Villela
  
  News & Views 08 Feb 2023
- The extent and drivers of global wetland loss
  
  An impressive combination of modelling and data analysis has enabled a new estimate of the extent of wetland losses over the past few centuries — and reveals that an area about the size of India has been lost since 1700.
  Nicholas J. Murray
  
  News & Views 08 Feb 2023
- An oracle predicts regulators of cell identity
  
  A computational tool called CellOracle can predict how networks of genes interact to program cell identity during embryonic development. The tool should help to hone efforts to understand how development is regulated.
  Jeffrey A. Farrell
  
  News & Views 08 Feb 2023
- A planetary ring in a surprising place
  
  An object in the distant Solar System has been shown to have a ring that is unusually far from its host — prompting speculation about how the ring material has avoided clumping together to form moons.
  Matthew M. Hedman
  
  News & Views 08 Feb 2023
- The brain’s encoding of warm and cool
  
  Research Briefing 08 Feb 2023
- Signs of ancient climate crisis as the Hittite empire unravelled
  Müge Durusu-Tanrıöver
  
  News & Views 08 Feb 2023
- From the archive: celebrating Faraday, and an appreciation of parasites
  
  News & Views 07 Feb 2023
- The Alzheimer’s risk gene APOE modulates the gut–brain axis
  Alfonso Martín-Peña
  Malú Gámez Tansey
  
  News & Views 06 Feb 2023

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Latest Research articles

The structural basis for HIV-1 Vif antagonism of human APOBEC3G

Yen-Li Li
Caroline A. Langley
John D. Gross
Article 08 Feb 2023
Aberrant phase separation and nucleolar dysfunction in rare genetic diseases

Frameshift mutations that create arginine-rich basic tails in transcription factors and other proteins can lead to altered phase separation in the nucleolus, which in turn leads to syndromes such as brachyphalangy, polydactyly and tibial aplasia.

Martin A. Mensah
Henri Niskanen
Denes Hnisz
Article Open Access 08 Feb 2023
An E1–E2 fusion protein primes antiviral immune signalling in bacteria

This study demonstrates that bacteria use a ubiquitin transferase-like enzyme to prime cGAS/DncV-like nucleotidyltransferase activation and use a deubiquitinase-like enzyme to decrease activity.

Hannah E. Ledvina
Qiaozhen Ye
Aaron T. Whiteley
Article 08 Feb 2023
Spin-polarized spatially indirect excitons in a topological insulator

A topological insulator, Bi₂Te₃, has been found to have spatially indirect spin-polarized excitonic states, opening the prospect of combining exciton and topological physics.

Ryo Mori
Samuel Ciocys
Alessandra Lanzara
Article 08 Feb 2023
TET2 guards against unchecked BATF3-induced CAR T cell expansion

Disruption of TET2 increases the antitumour efficacy of CAR T cells, but establishes an epigenetic state that is prone to hyperproliferation and accumulation of secondary mutations.

Nayan Jain
Zeguo Zhao
Michel Sadelain
Article 08 Feb 2023