West nile virus articles within Nature Communications

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  • Article
    | Open Access

    West Nile Virus is emerging as an important pathogen in Europe, likely driven by recent climate and land-use changes. Here, the authors estimate the extent of the climate change-driven impact by modelling the change in West Nile Virus ecological suitability across the continent in the absence of climate change.

    • Diana Erazo
    • , Luke Grant
    •  & Simon Dellicour
  • Article
    | Open Access

    West Nile virus is an animal pathogen that has spread rapidly in Europe in recent years, causing several human deaths. This study investigates the spatial and temporal dynamics of the virus circulation between Africa (its place of origin) and Europe.

    • Giulia Mencattelli
    • , Marie Henriette Dior Ndione
    •  & Giovanni Savini
  • Article
    | Open Access

    In this study, Lin and Zhao et al. show that type I IFN autoantibodies promote West Nile virus infection in enterocytes, which correlates with encephalitis disease risk in humans; while in mice, type I IFN signaling defects associate with gastrointestinal tract and blood-brain barrier permeability and disease severity.

    • Shih-Ching Lin
    • , Fang R. Zhao
    •  & Michael S. Diamond
  • Article
    | Open Access

    Classical epidemiological approaches have been limited in their ability to formally test hypotheses. Here, Dellicour et al. illustrate how phylodynamic and phylogeographic analyses can be leveraged for hypothesis testing in molecular epidemiology using West Nile virus in North America as an example.

    • Simon Dellicour
    • , Sebastian Lequime
    •  & Philippe Lemey