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Transmission electron microscopy is a general type of electron microscopy that generates an image of the internal structure of a thin sample using a beam of electrons to achieve much higher spatial resolution than light microscopy.
Significant challenges exist for structural characterization of enzymes responsible for biomineralization. Here the authors show that native mass spectrometry and high resolution electron microscopy can define the subunit topology and copper binding of a manganese oxidizing complex, and describe early stage formation of its mineral products
Beyond high resolving power, electron microscopy can be used to study both the electronic and magnetic properties of a sample. Here, Grillo et al. combine electron vortex beams with holographic detection to measure out-of-plane nanoscale magnetic fields.
By combining an electron-counting camera with low-energy transmission electron microscopy, it is possible to directly image the surface structure of delicate metal–organic framework crystals and their coherent interfaces.