Tissue engineering articles within Nature

Featured

  • Article
    | Open Access

    Topobiologically complex mini-colons—which enable the faithful in vitro recapitulation of colorectal cancer tumorigenesis and its environmental determinants—offer the possibility to reduce animal use in a wide range of experimental applications.

    • L. Francisco Lorenzo-Martín
    • , Tania Hübscher
    •  & Matthias P. Lutolf
  • Article
    | Open Access

    A genetically inducible stem cell-derived embryoid model of early post-implantation human embryogenesis captures the codevelopment of embryonic tissue and extra-embryonic endoderm and mesoderm niche with early haematopoiesis, with potential for drug testing and disease modelling.

    • Joshua Hislop
    • , Qi Song
    •  & Mo R. Ebrahimkhani
  • Article
    | Open Access

    Synthetic cell adhesion molecules yield customized cell–cell interactions with adhesion properties that are similar to native interactions, and offer abilities for cell and tissue engineering and for systematically studying multicellular organization.

    • Adam J. Stevens
    • , Andrew R. Harris
    •  & Wendell A. Lim
  • Letter |

    A new approach has been developed in order to achieve the stepwise differentiation of inner ear sensory epithelia from mouse embryonic stem cells in a three-dimensional culture: this process, which mimics normal development and produces cells that have functional characteristics of mechanosensitive hair cells, is hoped to provide further insights into inner ear development and disorder.

    • Karl R. Koehler
    • , Andrew M. Mikosz
    •  & Eri Hashino
  • Outlook |

    The donor lungs of the future — built from collagen or silicone rubber or engineered from donor organs stripped of their original cells — might give a new lease of life to COPD patients.

    • Elie Dolgin
  • News & Views |

    To understand how blood vessels form and function, scientists require reproducible systems that mimic living tissues. An innovative approach based on microfabricated vessels provides a key step towards this goal.

    • Claudio Franco
    •  & Holger Gerhardt
  • News Feature |

    With his knack for knowing what stem cells want, Yoshiki Sasai has grown an eye and parts of a brain in a dish.

    • David Cyranoski
  • Technology Feature |

    For years, scientists have struggled to reconstruct tissues and organs by combining cells and nanotechnology. These devices are now edging from cool concept to practical application.

    • Monya Baker
  • News Feature |

    Researchers are sure that they can put lab-grown meat on the menu — if they can just get cultured muscle cells to bulk up.

    • Nicola Jones
  • News |

    Implanted tissue and microchip mimic both perform functions of lung.

    • Alla Katsnelson