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Article
| Open Access
Cross-modality supervised image restoration enables nanoscale tracking of synaptic plasticity in living mice
XTC is a supervised deep-learning-based image-restoration approach that is trained with images from different modalities and applied to an in vivo modality with no ground truth. XTC’s capabilities are demonstrated in synapse tracking in the mouse brain.
- Yu Kang T. Xu
- , Austin R. Graves
- & Jeremias Sulam
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Tools in Brief |
A spotlight on synaptic plasticity
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Research Highlights |
Protein GPS
Antibody-like probes report the localization and amount of endogenous proteins in living cells.
- Erika Pastrana
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Research Highlights |
A back door to the neuron
An electrochemical gene-delivery method enables rapid modification of gene expression in postmitotic neurons in vivo, changing their identity and connectivity pattern.
- Erika Pastrana
Real-time visualization of structural dynamics of synapses in live cells in vivo