Standards

Definition

Standards in research refer to a specified level of quality or achievement. For example, in medical research, reporting standards have been drawn up to ensure authors of publications report everything necessary for a full understanding and replication of published research. Standards can also include agreed nomenclature or identifiers.

Latest Research and Reviews

  • Research | | open

    The Quest for Orthologs consortium compares the performance of a large number of established orthology inference methods on 20 benchmarks and provides a free web tool for methods developers to facilitate further benchmarking.

    • Adrian M Altenhoff
    • , Brigitte Boeckmann
    • , Salvador Capella-Gutierrez
    • , Daniel A Dalquen
    • , Todd DeLuca
    • , Kristoffer Forslund
    • , Jaime Huerta-Cepas
    • , Benjamin Linard
    • , Cécile Pereira
    • , Leszek P Pryszcz
    • , Fabian Schreiber
    • , Alan Sousa da Silva
    • , Damian Szklarczyk
    • , Clément-Marie Train
    • , Peer Bork
    • , Odile Lecompte
    • , Christian von Mering
    • , Ioannis Xenarios
    • , Kimmen Sjölander
    • , Lars Juhl Jensen
    • , Maria J Martin
    • , Matthieu Muffato
    • , Quest for Orthologs consortium
    • , Toni Gabaldón
    • , Suzanna E Lewis
    • , Paul D Thomas
    • , Erik Sonnhammer
    •  & Christophe Dessimoz
    Nature Methods 13, 425–430
  • Research | | open

    • Justin M. Zook
    • , David Catoe
    • , Jennifer McDaniel
    • , Lindsay Vang
    • , Noah Spies
    • , Arend Sidow
    • , Ziming Weng
    • , Yuling Liu
    • , Christopher E. Mason
    • , Noah Alexander
    • , Elizabeth Henaff
    • , Alexa B.R. McIntyre
    • , Dhruva Chandramohan
    • , Feng Chen
    • , Erich Jaeger
    • , Ali Moshrefi
    • , Khoa Pham
    • , William Stedman
    • , Tiffany Liang
    • , Michael Saghbini
    • , Zeljko Dzakula
    • , Alex Hastie
    • , Han Cao
    • , Gintaras Deikus
    • , Eric Schadt
    • , Robert Sebra
    • , Ali Bashir
    • , Rebecca M. Truty
    • , Christopher C. Chang
    • , Natali Gulbahce
    • , Keyan Zhao
    • , Srinka Ghosh
    • , Fiona Hyland
    • , Yutao Fu
    • , Mark Chaisson
    • , Chunlin Xiao
    • , Jonathan Trow
    • , Stephen T. Sherry
    • , Alexander W. Zaranek
    • , Madeleine Ball
    • , Jason Bobe
    • , Preston Estep
    • , George M. Church
    • , Patrick Marks
    • , Sofia Kyriazopoulou-Panagiotopoulou
    • , Grace X.Y. Zheng
    • , Michael Schnall-Levin
    • , Heather S. Ordonez
    • , Patrice A. Mudivarti
    • , Kristina Giorda
    • , Ying Sheng
    • , Karoline Bjarnesdatter Rypdal
    •  & Marc Salit
    Scientific Data 3, 160025
  • Research | | open

    The first report of the ICGC-TCGA DREAM Somatic Mutation Calling Challenge introduces the BAMSurgeon tool for accurate tumor simulation and reports the performance of 248 submissions in calling single-nucleotide variants from three pairs of synthetic tumor–normal genome benchmarks.

    • Adam D Ewing
    • , Kathleen E Houlahan
    • , Yin Hu
    • , Kyle Ellrott
    • , Cristian Caloian
    • , Takafumi N Yamaguchi
    • , J Christopher Bare
    • , Christine P'ng
    • , Daryl Waggott
    • , Veronica Y Sabelnykova
    • , ICGC-TCGA DREAM Somatic Mutation Calling Challenge participants
    • , Michael R Kellen
    • , Thea C Norman
    • , David Haussler
    • , Stephen H Friend
    • , Gustavo Stolovitzky
    • , Adam A Margolin
    • , Joshua M Stuart
    •  & Paul C Boutros
    Nature Methods 12, 623–630
  • Protocols |

    This protocol summarizes the recommendations developed after a comparison of Elispot plate-reading approaches by a panel of laboratories and subsequent agreement regarding the optimal steps to follow when evaluating Elispot plates.

    • Sylvia Janetzki
    • , Leah Price
    • , Helene Schroeder
    • , Cedrik M Britten
    • , Marij J P Welters
    •  & Axel Hoos
    Nature Protocols 10, 1098–1115

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