Skin manifestations articles within Nature Communications

Featured

• Article
  17 June 2021 | Open Access

  Single-cell RNA-seq reveals fibroblast heterogeneity and increased mesenchymal fibroblasts in human fibrotic skin diseases

  Fibroblasts are found to be heterogeneous in multiple fibrotic diseases, but fibroblast heterogeneity in fibrotic skin diseases is not well characterized. Here the authors employ scRNA-seq to explore fibroblast heterogeneity in keloid, a paradigm of fibrotic skin diseases.

  • Cheng-Cheng Deng
  • , Yong-Fei Hu
  •  & Bin Yang

• Article
  10 November 2016 | Open Access

  Hyperglycaemia inhibits REG3A expression to exacerbate TLR3-mediated skin inflammation in diabetes

  Patients with diabetes often have delayed wound healing, associated with excessive inflammation. Here the authors report that REG3A inhibits TLR3-driven inflammation in skin wounds, and show that REG3A is reduced in models of diabetes, which exacerbates inflammation in diabetic wounds.

  • Yelin Wu
  • , Yanchun Quan
  •  & Yuping Lai

• Article
  06 November 2015 | Open Access

  Meta-analysis identifies seven susceptibility loci involved in the atopic march

  The development of asthma following eczema is known as the atopic march. Here the authors conduct a GWAS on affected children and identify two novel loci associated with the disease phenotype.

  • Ingo Marenholz
  • , Jorge Esparza-Gordillo
  •  & Young Ae Lee

• Article | 17 March 2015

  Impedance sensing device enables early detection of pressure ulcers in vivo

  Sustained pressure on the skin reduces blood flow and causes wounds. Here the authors describe a flexible electronic ‘bandage’ that measures changes in tissue impedance spectra and detects early tissue damage in rats before it can be visualized, thus enabling possible prevention of pressure ulcers.

  • Sarah L. Swisher
  • , Monica C. Lin
  •  & Michel M. Maharbiz