Sarcoma articles within Nature

Featured

• Article | 15 January 2020

  B cells are associated with survival and immunotherapy response in sarcoma

  Immune profiling of the tumour microenvironment of soft-tissue sarcoma identifies a group of patients with high levels of B-cell infiltration and tertiary lymphoid structures that have improved survival and a high response rate to immune checkpoint blockade therapy.

  • Florent Petitprez
  • , Aurélien de Reyniès
  •  & Wolf H. Fridman

• Letter | 05 July 2017

  Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

  Therapy-resistant cancer cell states identified across diverse contexts are selectively vulnerable to ferroptotic cell death induced by inhibition of lipid peroxidase pathways converging on GPX4.

  • Vasanthi S. Viswanathan
  • , Matthew J. Ryan
  •  & Stuart L. Schreiber

• Letter | 08 February 2012

  Expression of tumour-specific antigens underlies cancer immunoediting

  This paper illustrates that immunosurveillance and immunoediting can occur in an oncogene-driven endogenous tumour model provided that the tumours carry strong neoantigens not present in the host.

  • Michel DuPage
  • , Claire Mazumdar
  •  & Tyler Jacks

• Research Highlights | 30 June 2010

  Cancer genomics: Prognostic sign