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| Open AccessIdentification and motif analyses of candidate nonreceptor olfactory genes of Dendroctonus adjunctus Blandford (Coleoptera: Curculionidae) from the head transcriptome
- Brenda Torres-Huerta
- , Obdulia L. Segura-León
- & Héctor González-Hernández
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| Open AccessThe physical origin of rate promoting vibrations in enzymes revealed by structural rigidity
- Yann Chalopin
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| Open AccessMolecular simulations unravel the molecular principles that mediate selective permeability of carboxysome shell protein
- Matthew Faulkner
- , István Szabó
- & Lu-Ning Liu
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| Open AccessMechanistic insights into the loss-of-function mechanisms of rare human D-amino acid oxidase variants implicated in amyotrophic lateral sclerosis
- Aditya K. Padhi
- & Kam Y. J. Zhang
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| Open AccessDesigning a multi-epitope peptide based vaccine against SARS-CoV-2
- Abhishek Singh
- , Mukesh Thakur
- & Kailash Chandra
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| Open AccessEffect of sequence padding on the performance of deep learning models in archaeal protein functional prediction
- Angela Lopez-del Rio
- , Maria Martin
- & Rabie Saidi
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| Open AccessNearest-neighbor amino acids of specificity-determining residues influence the activity of engineered Cre-type recombinases
- Anjali Soni
- , Martina Augsburg
- & M. Teresa Pisabarro
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| Open AccessAntibody-protein binding and conformational changes: identifying allosteric signalling pathways to engineer a better effector response
- Mohammed M. Al Qaraghuli
- , Karina Kubiak-Ossowska
- & Paul A. Mulheran
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| Open AccessZinc-mediated conformational preselection mechanism in the allosteric control of DNA binding to the zinc transcriptional regulator (ZitR)
- Xinheng He
- , Duan Ni
- & Shaoyong Lu
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| Open AccessThe structural basis of the genetic code: amino acid recognition by aminoacyl-tRNA synthetases
- Florian Kaiser
- , Sarah Krautwurst
- & Michael Schroeder
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| Open AccessInvestigating the pathogenic SNPs in BLM helicase and their biological consequences by computational approach
- Faisal A. Alzahrani
- , Firoz Ahmed
- & Mohammad Sarwar Jamal
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| Open AccessHAPPENN is a novel tool for hemolytic activity prediction for therapeutic peptides which employs neural networks
- Patrick Brendan Timmons
- & Chandralal M. Hewage
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| Open AccessIncorporating hybrid models into lysine malonylation sites prediction on mammalian and plant proteins
- Chia-Ru Chung
- , Ya-Ping Chang
- & Tzong-Yi Lee
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| Open AccessPhylogeny, evolution, and potential ecological relationship of cytochrome CYP52 enzymes in Saccharomycetales yeasts
- Jossue Ortiz-Álvarez
- , Arturo Becerra-Bracho
- & César Hernández-Rodríguez
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| Open AccessTwo-Level Protein Methylation Prediction using structure model-based features
- Wei Zheng
- , Qiqige Wuyun
- & Yanping Zhang
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| Open AccessStructural and evolutionary analyses of the Plasmodium falciparum chloroquine resistance transporter
- Romain Coppée
- , Audrey Sabbagh
- & Jérôme Clain
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| Open AccessDelineating elastic properties of kinesin linker and their sensitivity to point mutations
- Michał Świątek
- & Ewa Gudowska-Nowak
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| Open AccessMechanistic insights into the deleterious roles of Nasu-Hakola disease associated TREM2 variants
- Raju Dash
- , Ho Jin Choi
- & Il Soo Moon
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| Open AccessPIPE4: Fast PPI Predictor for Comprehensive Inter- and Cross-Species Interactomes
- Kevin Dick
- , Bahram Samanfar
- & James R. Green
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| Open AccessStructural characterization and in-silico analysis of Momordica charantia 7S globulin for stability and ACE inhibition
- Pooja Kesari
- , Shivendra Pratap
- & Pravindra Kumar
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| Open AccessISOGO: Functional annotation of protein-coding splice variants
- Juan A Ferrer-Bonsoms
- , Ignacio Cassol
- & Angel Rubio
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| Open AccessPatterns of diverse gene functions in genomic neighborhoods predict gene function and phenotype
- Matej Mihelčić
- , Tomislav Šmuc
- & Fran Supek
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| Open AccessOutCyte: a novel tool for predicting unconventional protein secretion
- Linlin Zhao
- , Gereon Poschmann
- & Kai Stühler
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| Open AccessCosolvent Analysis Toolkit (CAT): a robust hotspot identification platform for cosolvent simulations of proteins to expand the druggable proteome
- Francesc Sabanés Zariquiey
- , João V. de Souza
- & Agnieszka K. Bronowska
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| Open AccessNNTox: Gene Ontology-Based Protein Toxicity Prediction Using Neural Network
- Aashish Jain
- & Daisuke Kihara
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| Open AccessMolecular Dynamics Simulation reveals the mechanism by which the Influenza Cap-dependent Endonuclease acquires resistance against Baloxavir marboxil
- Ryunosuke Yoshino
- , Nobuaki Yasuo
- & Masakazu Sekijima
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| Open AccessParticle Mobility Analysis Using Deep Learning and the Moment Scaling Spectrum
- Marloes Arts
- , Ihor Smal
- & Erik Meijering
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| Open AccessCharacterization and Identification of Lysine Succinylation Sites based on Deep Learning Method
- Kai-Yao Huang
- , Justin Bo-Kai Hsu
- & Tzong-Yi Lee
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| Open AccessMolecular insights into the interaction of hemorphin and its targets
- Amanat Ali
- , Bincy Baby
- & Ranjit Vijayan
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| Open AccessAnalysis of mutations leading to para-aminosalicylic acid resistance in Mycobacterium tuberculosis
- Bharati Pandey
- , Sonam Grover
- & Abhinav Grover
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| Open AccessTensor Algebra-based Geometrical (3D) Biomacro-Molecular Descriptors for Protein Research: Theory, Applications and Comparison with other Methods
- Julio E. Terán
- , Yovani Marrero-Ponce
- & F. Javier Torres
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| Open AccessTryptophan Oxidation in the UQCRC1 Subunit of Mitochondrial Complex III (Ubiquinol-Cytochrome C Reductase) in a Mouse Model of Myodegeneration Causes Large Structural Changes in the Complex: A Molecular Dynamics Simulation Study
- Sruthi Unni
- , S. Thiyagarajan
- & B. Padmanabhan
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| Open AccessComparative structural and evolutionary analyses predict functional sites in the artemisinin resistance malaria protein K13
- Romain Coppée
- , Daniel C. Jeffares
- & Jérôme Clain
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| Open AccessIdentification and Characterization of Genetic Determinants of Isoniazid and Rifampicin Resistance in Mycobacterium tuberculosis in Southern India
- Asma Munir
- , Narender Kumar
- & Sony Malhotra
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| Open AccessComparative genomics of chytrid fungi reveal insights into the obligate biotrophic and pathogenic lifestyle of Synchytrium endobioticum
- Bart T. L. H. van de Vossenberg
- , Sven Warris
- & Theo A. J. van der Lee
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| Open AccessComputational identification of microbial phosphorylation sites by the enhanced characteristics of sequence information
- Md. Mehedi Hasan
- , Md. Mamunur Rashid
- & Hiroyuki Kurata
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| Open AccessDEEPred: Automated Protein Function Prediction with Multi-task Feed-forward Deep Neural Networks
- Ahmet Sureyya Rifaioglu
- , Tunca Doğan
- & Volkan Atalay
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| Open AccessStructural bases of peptidoglycan recognition by lysostaphin SH3b domain
- Paweł Mitkowski
- , Elżbieta Jagielska
- & Izabela Sabała
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| Open AccessMolecular Dynamics Simulations of the Allosteric Modulation of the Adenosine A2a Receptor by a Mini-G Protein
- Pedro Renault
- , Maxime Louet
- & Nicolas Floquet
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| Open AccessComputational analysis of the evolutionarily conserved Missing In Metastasis/Metastasis Suppressor 1 gene predicts novel interactions, regulatory regions and transcriptional control
- Petar Petrov
- , Alexey V. Sarapulov
- & Pieta K. Mattila
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| Open AccessProbabilistic variable-length segmentation of protein sequences for discriminative motif discovery (DiMotif) and sequence embedding (ProtVecX)
- Ehsaneddin Asgari
- , Alice C. McHardy
- & Mohammad R. K. Mofrad
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| Open AccessBioinformatic discovery of a toxin family in Chryseobacterium piperi with sequence similarity to botulinum neurotoxins
- Michael James Mansfield
- , Travis Gwynn Wentz
- & Andrew Charles Doxey
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| Open AccessMycobacterium tuberculosis Rv0366c-Rv0367c encodes a non-canonical PezAT-like toxin-antitoxin pair
- Himani Tandon
- , Arun Sharma
- & Ramandeep Singh
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| Open AccessImmunoinformatic and systems biology approaches to predict and validate peptide vaccines against Epstein–Barr virus (EBV)
- Arif Ali
- , Abbas Khan
- & Dong-Qing Wei
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| Open AccessDeciphering the Potential Pharmaceutical Mechanism of GUI-ZHI-FU-LING-WAN on Systemic Sclerosis based on Systems Biology Approaches
- Qiao Wang
- , Guoshan Shi
- & Lin Huang
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| Open AccessThe reduced activity of PP-1α under redox stress condition is a consequence of GSH-mediated transient disulfide formation
- Simranjit Singh
- , Simon Lämmle
- & Florian Richter
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| Open AccessDynamic recognition and linkage specificity in K63 di-ubiquitin and TAB2 NZF domain complex
- Kei Moritsugu
- , Hafumi Nishi
- & Akinori Kidera
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| Open AccessPrediction of high anti-angiogenic activity peptides in silico using a generalized linear model and feature selection
- Jose Liñares Blanco
- , Ana B. Porto-Pazos
- & Carlos Fernandez-Lozano
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| Open AccessDeep-RBPPred: Predicting RNA binding proteins in the proteome scale based on deep learning
- Jinfang Zheng
- , Xiaoli Zhang
- & Shiyong Liu