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| Open AccessCRISPR-mediated gene targeting of CK1δ/ε leads to enhanced understanding of their role in endocytosis via phosphoregulation of GAPVD1
- Rodrigo X. Guillen
- , Janel R. Beckley
- & Kathleen L. Gould
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| Open AccessMG132 exerts anti-viral activity against HSV-1 by overcoming virus-mediated suppression of the ERK signaling pathway
- Hanako Ishimaru
- , Kohei Hosokawa
- & Masahiro Fujimuro
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| Open AccessHigh glucose induces phosphorylation and oxidation of mitochondrial proteins in renal tubular cells: A proteomics approach
- Siripat Aluksanasuwan
- , Sirikanya Plumworasawat
- & Visith Thongboonkerd
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| Open AccessIdentification and functional characterisation of N-linked glycosylation of the orphan G protein-coupled receptor Gpr176
- Tianyu Wang
- , Shumpei Nakagawa
- & Masao Doi
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| Open AccessThe Two-Species Model of transketolase explains donor substrate-binding, inhibition and heat-activation
- Henry C. Wilkinson
- & Paul A. Dalby
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| Open AccessGenome-wide screening reveals a role for subcellular localization of CRBN in the anti-myeloma activity of pomalidomide
- Shumpei Tateno
- , Midori Iida
- & Yuki Yamaguchi
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| Open AccessSialylated N-glycan profile during acute and chronic infections with Toxoplasma gondii in mice
- Ibrahim Farag Rehan
- , Motamed Elsayed Mahmoud
- & Abd El-Latif Hesham
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| Open Accessp38 MAPK signalling regulates cytokine production in IL-33 stimulated Type 2 Innate Lymphoid cells
- Tsvetana Petrova
- , Jelena Pesic
- & J. Simon C. Arthur
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| Open AccessIdentification of a novel trigger complex that facilitates ribosome-associated quality control in mammalian cells
- Satoshi Hashimoto
- , Takato Sugiyama
- & Toshifumi Inada
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| Open AccessHistone demethylase KDM4D cooperates with NFIB and MLL1 complex to regulate adipogenic differentiation of C3H10T1/2 mesenchymal stem cells
- Jang Hyun Choi
- & Hansol Lee
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| Open AccessUV oxidation of cyclic AMP receptor protein, a global bacterial gene regulator, decreases DNA binding and cleaves DNA at specific sites
- Fabian Leinisch
- , Michele Mariotti
- & Michael J. Davies
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| Open AccessMitochondrial MUL1 E3 ubiquitin ligase regulates Hypoxia Inducible Factor (HIF-1α) and metabolic reprogramming by modulating the UBXN7 cofactor protein
- Lucia Cilenti
- , Jacopo Di Gregorio
- & Antonis S. Zervos
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| Open AccessBinding of myeloperoxidase to the extracellular matrix of smooth muscle cells and subsequent matrix modification
- Huan Cai
- , Christine Y. Chuang
- & Michael J. Davies
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| Open AccessTargeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation
- Sylwia Jones
- , Peter J. King
- & Daniel Hochhauser
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| Open AccessA C-terminal Pfs48/45 malaria transmission-blocking vaccine candidate produced in the baculovirus expression system
- Shwu-Maan Lee
- , John M. Hickey
- & Jordan L. Plieskatt
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| Open AccessHaspin-dependent and independent effects of the kinase inhibitor 5-Iodotubercidin on self-renewal and differentiation
- Eleftheria Karanika
- , Katerina Soupsana
- & Spyros Georgatos
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| Open AccessTroponin destabilization impairs sarcomere-cytoskeleton interactions in iPSC-derived cardiomyocytes from dilated cardiomyopathy patients
- Yuanyuan Dai
- , Asset Amenov
- & Antje Ebert
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| Open AccessNucleus-specific linker histones Hho1 and Mlh1 form distinct protein interactions during growth, starvation and development in Tetrahymena thermophila
- Syed Nabeel-Shah
- , Kanwal Ashraf
- & Jeffrey Fillingham
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| Open AccessInflammatory bowel disease-associated ubiquitin ligase RNF183 promotes lysosomal degradation of DR5 and TRAIL-induced caspase activation
- Yan Wu
- , Yuka Kimura
- & Masayuki Kaneko
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| Open AccessCollagen fragments quantified in serum as measures of desmoplasia associate with survival outcome in patients with advanced pancreatic cancer
- Nicholas Willumsen
- , Suhail M. Ali
- & Allan Lipton
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| Open AccessA negative feedback mechanism links UBC gene expression to ubiquitin levels by affecting RNA splicing rather than transcription
- Marzia Bianchi
- , Rita Crinelli
- & Mauro Magnani
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| Open AccessIdentification of potential chemosignals in the European water vole Arvicola terrestris
- Patricia Nagnan-Le Meillour
- , Amandine Descamps
- & Matthieu Keller
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| Open AccessUntargeted histone profiling during naive conversion uncovers conserved modification markers between mouse and human
- Laura De Clerck
- , Jasin Taelman
- & Maarten Dhaenens
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| Open AccessUnconventional secretion of α-Crystallin B requires the Autophagic pathway and is controlled by phosphorylation of its serine 59 residue
- M. D’Agostino
- , G. Scerra
- & M. Renna
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| Open AccessUbiquitylation and endocytosis of the human LAT1/SLC7A5 amino acid transporter
- Céline Barthelemy
- & Bruno André
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| Open AccessQuantification of intracellular N-terminal β-actin arginylation
- Li Chen
- & Anna Kashina
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| Open AccessSerotonin 5-HT2C Receptor Cys23Ser Single Nucleotide Polymorphism Associates with Receptor Function and Localization In Vitro
- Michelle A. Land
- , Holly L. Chapman
- & Noelle C. Anastasio
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| Open AccessRNF34 overexpression exacerbates neurological deficits and brain injury in a mouse model of intracerebral hemorrhage by potentiating mitochondrial dysfunction-mediated oxidative stress
- Xin Qu
- , Ning Wang
- & Weitao Cheng
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| Open AccessDifferential Inhibition of Human and Trypanosome Ubiquitin E1S by TAK-243 Offers Possibilities for Parasite Selective Inhibitors
- D. Roeland Boer
- & Marie-José Bijlmakers
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| Open AccessRetinoid receptor turnover mediated by sumoylation, ubiquitination and the valosin-containing protein is disrupted in glioblastoma
- Virginia Rodriguez
- , Rolanda Bailey
- & Mark R. Gilbert
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| Open AccessAcetylation of conserved DVL-1 lysines regulates its nuclear translocation and binding to gene promoters in triple-negative breast cancer
- Monica Sharma
- , Deborah Molehin
- & Kevin Pruitt
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| Open AccessSQSTM-1/p62 potentiates HTLV-1 Tax-mediated NF-κB activation through its ubiquitin binding function
- Aurélien Schwob
- , Elodie Teruel
- & Chloé Journo
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| Open AccessThe Protein Arginine Methyltransferases 1 and 5 affect Myc properties in glioblastoma stem cells
- Annarita Favia
- , Luisa Salvatori
- & Barbara Illi
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| Open AccessRegulation of Respiration and Apoptosis by Cytochrome c Threonine 58 Phosphorylation
- Junmei Wan
- , Hasini A. Kalpage
- & Maik Hüttemann
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| Open AccessMechanism and Consequences of The Impaired Hif-1α Response to Hypoxia in Human Proximal Tubular HK-2 Cells Exposed to High Glucose
- Coral García-Pastor
- , Selma Benito-Martínez
- & Francisco Javier Lucio-Cazaña
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| Open AccessThe subcellular localization of bHLH transcription factor TCF4 is mediated by multiple nuclear localization and nuclear export signals
- Beata Greb-Markiewicz
- , Wioletta Kazana
- & Andrzej Ożyhar
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| Open AccessS-nitrosoglutathione inhibits adipogenesis in 3T3-L1 preadipocytes by S-nitrosation of CCAAT/enhancer-binding protein β
- Marion Mussbacher
- , Heike Stessel
- & Astrid Schrammel
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| Open AccessTFEB activates Nrf2 by repressing its E3 ubiquitin ligase DCAF11 and promoting phosphorylation of p62
- Jee-Yun Park
- , Sunhyo Kim
- & Chulman Jo
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| Open AccessSynthetic PreImplantation Factor (sPIF) induces posttranslational protein modification and reverses paralysis in EAE mice
- Soren Hayrabedyan
- , Reut Shainer
- & Martin Mueller
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| Open AccessBinding to medium and long chain fatty acyls is a common property of HEAT and ARM repeat modules
- Tie-Mei Li
- , John P. Coan
- & Katrin F. Chua
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| Open AccessS-Glutathionylated Serine Proteinase Inhibitors as Biomarkers for Radiation Exposure in Prostate Cancer Patients
- Leilei Zhang
- , Jie Zhang
- & Kenneth D. Tew
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| Open AccessA mass spectrometry-based assay using metabolic labeling to rapidly monitor chromatin accessibility of modified histone proteins
- Simone Sidoli
- , Mariana Lopes
- & Benjamin A. Garcia
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| Open AccessAnalyzing expression and phosphorylation of the EGF receptor in HNSCC
- Malte Kriegs
- , Till Sebastian Clauditz
- & Adrian Münscher
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| Open AccessMultilevel structure–activity profiling reveals multiple green tea compound families that each modulate ubiquitin-activating enzyme and ubiquitination by a distinct mechanism
- Gabriel Fenteany
- , Paras Gaur
- & Lajos Haracska
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| Open AccessCalcineurin regulates cyclin D1 stability through dephosphorylation at T286
- Takahiro Goshima
- , Makoto Habara
- & Midori Shimada
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| Open AccessPhosphorylation-dependent modulation of CFTR macromolecular signalling complex activity by cigarette smoke condensate in airway epithelia
- Andrea Schnúr
- , Aiswarya Premchandar
- & Gergely L. Lukacs
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| Open AccessProximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins
- Sascha E. Dho
- , Nancy Silva-Gagliardi
- & C. Jane McGlade
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| Open AccessNuclear and cytoplasmic WDR-23 isoforms mediate differential effects on GEN-1 and SKN-1 substrates
- Brett N. Spatola
- , Jacqueline Y. Lo
- & Sean P. Curran
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| Open AccessEstablishment of serine protease htrA mutants in Helicobacter pylori is associated with secA mutations
- Anna Zawilak-Pawlik
- , Urszula Zarzecka
- & Joanna Skorko-Glonek