Population genetics

Definition

Population genetics is the study of the genetic composition of populations, including distributions and changes in genotype and phenotype frequency in response to the processes of natural selection, genetic drift, mutation and gene flow.

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Latest Research and Reviews

  • Research | | open

    People of Mexico have diverse historical and genetic background. Here, Romero-Hidalgo and colleagues sequence whole genomes of Native Americans of Mexico, and show demographic history and genetic variation shared among subgroups of Native Americans.

    • Sandra Romero-Hidalgo
    • , Adrián Ochoa-Leyva
    • , Alejandro Garcíarrubio
    • , Victor Acuña-Alonzo
    • , Erika Antúnez-Argüelles
    • , Martha Balcazar-Quintero
    • , Rodrigo Barquera-Lozano
    • , Alessandra Carnevale
    • , Fernanda Cornejo-Granados
    • , Juan Carlos Fernández-López
    • , Rodrigo García-Herrera
    • , Humberto García-Ortíz
    • , Ángeles Granados-Silvestre
    • , Julio Granados
    • , Fernando Guerrero-Romero
    • , Enrique Hernández-Lemus
    • , Paola León-Mimila
    • , Gastón Macín-Pérez
    • , Angélica Martínez-Hernández
    • , Marta Menjivar
    • , Enrique Morett
    • , Lorena Orozco
    • , Guadalupe Ortíz-López
    • , Fernando Pérez-Villatoro
    • , Javier Rivera-Morales
    • , Fernando Riveros-McKay
    • , Marisela Villalobos-Comparán
    • , Hugo Villamil-Ramírez
    • , Teresa Villarreal-Molina
    • , Samuel Canizales-Quinteros
    •  & Xavier Soberón
  • Research | | open

    Obsessive-compulsive disorder (OCD) is a neuropsychiatric disorder with symptoms including intrusive thoughts and time-consuming repetitive behaviors. Here Noh and colleagues identify genes enriched for functional variants associated with increased risk of OCD.

    • Hyun Ji Noh
    • , Ruqi Tang
    • , Jason Flannick
    • , Colm O’Dushlaine
    • , Ross Swofford
    • , Daniel Howrigan
    • , Diane P. Genereux
    • , Jeremy Johnson
    • , Gerard van Grootheest
    • , Edna Grünblatt
    • , Erik Andersson
    • , Diana R. Djurfeldt
    • , Paresh D. Patel
    • , Michele Koltookian
    • , Christina M. Hultman
    • , Michele T. Pato
    • , Carlos N. Pato
    • , Steven A. Rasmussen
    • , Michael A. Jenike
    • , Gregory L. Hanna
    • , S. Evelyn Stewart
    • , James A. Knowles
    • , Stephan Ruhrmann
    • , Hans-Jörgen Grabe
    • , Michael Wagner
    • , Christian Rück
    • , Carol A. Mathews
    • , Susanne Walitza
    • , Daniëlle C. Cath
    • , Guoping Feng
    • , Elinor K. Karlsson
    •  & Kerstin Lindblad-Toh

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