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| Open AccessFunctional DNA-based cytoskeletons for synthetic cells
Cytoskeletons are essential components of cells that perform a variety of tasks, and artificial cytoskeletons that perform these functions are required for the bottom-up assembly of synthetic cells. Now, a multi-functional cytoskeleton mimic has been engineered from DNA, consisting of confined DNA filaments that are capable of reversible self-assembly and transport of gold nanoparticles and vesicular cargo.
- Pengfei Zhan
- , Kevin Jahnke
- & Kerstin Göpfrich
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Direct knock-on of desolvated ions governs strict ion selectivity in K+ channels
That K+ channels conduct K+ ions at near-diffusion limited rates, but block the passage of smaller Na+ ions, creates an apparent contradiction. Now, atomistic simulations and free-energy calculations are used to show that both K+ permeation and ion selectivity are governed by the direct knock-on of completely desolvated ions in the channels’ selectivity filter.
- Wojciech Kopec
- , David A. Köpfer
- & Ulrich Zachariae
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Enhancement of anhydrous proton transport by supramolecular nanochannels in comb polymers
Efficient conduction of protons on a micrometre scale is critical for the development of fuel cell membranes — a key component of clean energy sources. Now, self-assembling amphiphilic polymers have been shown to provide a nanoscale organization of proton-conducting functionalities that dramatically increases anhydrous proton conductivity.
- Yangbin Chen
- , Michael Thorn
- & S. Thayumanavan