This Month |
Featured
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Article |
EthoLoop: automated closed-loop neuroethology in naturalistic environments
EthoLoop enables real-time tracking and behavioral analysis of animals in naturalistic environments and can be combined with behavioral conditioning, optogenetic stimulation or wireless recording of neural activity. The system is illustrated with freely behaving mice and mouse lemurs.
- Ali Nourizonoz
- , Robert Zimmermann
- & Daniel Huber
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Research Highlight |
Venomous organoids
Snake venom gland organoids provide a glimpse into the cell biology of the respective organ and serve as a platform for producing snake toxins.
- Nina Vogt
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Research Highlights |
Coral-on-a-chip
A miniature platform for studying corals at microscale resolution sheds new light on their biology.
- Vesna Todorovic
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This Month |
Stefan Kappe
A way to generate recombinant progeny of Plasmodium falciparum for genetics experiments, and the virtues of scuba diving.
- Vivien Marx
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Brief Communication |
Plasmodium falciparum genetic crosses in a humanized mouse model
A human-liver chimeric mouse supports the growth of recombinant Plasmodium falciparum progeny, enabling easy analysis of genetic crosses between parasite strains.
- Ashley M Vaughan
- , Richard S Pinapati
- & Stefan H I Kappe
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Methods in Brief |
Engineering the mosquito genome
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Tools in Brief |
Enter the diatom
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News & Views |
Animal identification with robot rovers
Robots can be used to detect marked animals with less disturbance when assessing ecological drivers of population change.
- Philip N Trathan
- & Louise Emmerson
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Brief Communication |
Efficient CRISPR-Cas9–mediated genome editing in Plasmodium falciparum
Single guide RNAs driven by a T7 promoter target Cas9 to two endogenous loci, leading to fast and efficient genome editing in the malaria parasite P. falciparum.
- Jeffrey C Wagner
- , Randall J Platt
- & Jacquin C Niles
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Methods in Brief |
Using single-cell genomics to understand malaria
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Tools in Brief |
Tools for salamander research
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Research Highlights |
Fishing for fluorescent proteins
The first fluorescent protein cloned from a vertebrate species is a promising tool for clinical diagnostics and research.
- Michael Eisenstein
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Tools in Brief |
Forward genetics in nonmodel species
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Research Highlights |
How to spot a cheetah
A gene-counting method can be used to profile gene expression differences in an organism that lacks a sequenced genome.
- Tal Nawy