Neural stem cells articles within Nature Materials

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• News & Views | 01 December 2017

  Making way for neural stemness

  The influence of matrix stiffness and degradation on neural progenitor cell stemness was investigated in a three-dimensional culture system, highlighting the role of remodelling in enhancing cell-to-cell interaction and ultimately maintaining neural stemness.

  • Phillip H. Kang
  • , Sanjay Kumar
  •  & David V. Schaffer

• Article | 30 October 2017

  Maintenance of neural progenitor cell stemness in 3D hydrogels requires matrix remodelling

  The physical properties of biomaterials affect cell behaviour. Here, the authors investigate how stiffness and degradation of hydrogels affect signalling pathways that modulate the maintenance of stemness of neural progenitor cells.

  • Christopher M. Madl
  • , Bauer L. LeSavage
  •  & Sarah C. Heilshorn