Nephrology articles within Nature Reviews Endocrinology

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  • Review Article |

    The current increasing rates of obesity are paralleled by a rise in the prevalence of chronic kidney disease. This Review outlines the potential mechanisms by which obesity might influence kidney function, but also presents evidence for the regulation of body weight by the kidney.

    • Kevin Yau
    • , Rachel Kuah
    •  & Tony K. T. Lam

  • Review Article |

    The renin–angiotensin–aldosterone system (RAAS) regulates blood pressure homeostasis via multiple mechanisms that act on a variety of organs. The development of drugs that target RAAS components is an active area of research. The authors of this Review discuss current and future therapeutic manipulation of the RAAS and its promise in improving the care of patients with hypertension.

    • Cesar A. Romero
    • , Marcelo Orias
    •  & Matthew R. Weir

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