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| Open AccessAlarmin S100A8/S100A9 as a biomarker for molecular imaging of local inflammatory activity
Alarmins are locally released during inflammation and are early amplifiers of inflammation. Here Vogl et al.show that the alarmin S100A8/S100A9 can be used as a sensitive marker to detect subclinical inflammation and follow disease progression in a variety of disease models.
- Thomas Vogl
- , Michel Eisenblätter
- & Johannes Roth
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Singlet oxygen triplet energy transfer-based imaging technology for mapping protein–protein proximity in intact cells
Fluorescence imaging can be used for the characterization of protein interactions in cells, although typical methods require the interacting groups to be quite close. Here, the authors present a fluorescent technique using singlet oxygen for the imaging of more distant protein–protein interactions.
- Tsz-Leung To
- , Michael J. Fadul
- & Xiaokun Shu
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Super-resolution surface mapping using the trajectories of molecular probes
Surface characterization of soft materialsin situis challenging due to the importance of non-covalent interactions. Now, a new chemical imaging method is reported that generates images of surface interactions by combining many molecular probe trajectories.
- Robert Walder
- , Nathaniel Nelson
- & Daniel K. Schwartz