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Non-fluorescent transient states of tyrosine as a basis for label-free protein conformation and interaction studies
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Time dependent dihedral angle oscillations of the spike protein of SARS-CoV-2 reveal favored frequencies of dihedral angle rotations
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Binding behavior of receptor binding domain of the SARS-CoV-2 virus and ivermectin
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Cardiac desmosomal adhesion relies on ideal-, slip- and catch bonds
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Revealing the mechanistic interactions of profenofos and captan pesticides with serum protein via biophysical and computational investigations
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Effect of histidine protonation state on ligand binding at the ATP-binding site of human protein kinase CK2
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Using deep learning and molecular dynamics simulations to unravel the regulation mechanism of peptides as noncompetitive inhibitor of xanthine oxidase
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Evaluating sheep hemoglobins with MD simulations as an animal model for sickle cell disease
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Structural and biophysical comparisons of the pomalidomide- and CC-220-induced interactions of SALL4 with cereblon
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An α-chain modification rivals the effect of fetal hemoglobin in retarding the rate of sickle cell fiber formation
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In-silico study of drug delivery to atherosclerosis in the human carotid artery using metal–organic frameworks based on adhesion of nanocarriers
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Human cystatin C induces the disaggregation process of selected amyloid beta peptides: a structural and kinetic view
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A deazariboflavin chromophore kinetically stabilizes reduced FAD state in a bifunctional cryptochrome
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Cells solved the Gibbs paradox by learning to contain entropic forces
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Decoding the dual recognition mechanism of the glucocorticoid receptor for DNA and RNA: sequence versus shape
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Benchmarking of force fields to characterize the intrinsically disordered R2-FUS-LC region
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Determining the structure of the bacterial voltage-gated sodium channel NaChBac embedded in liposomes by cryo electron tomography and subtomogram averaging
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Advantages and potential limitations of applying AFM kymograph analysis to pharmaceutically relevant membrane proteins in lipid bilayers
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Growth factors and mechano-regulated reciprocal crosstalk with extracellular matrix tune the keratocyte–fibroblast/myofibroblast transition
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Mechanosensitive traction force generation is regulated by the neutrophil activation state
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Modelling ligand depletion for simultaneous affinity and binding site quantification on cells and tissue
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Designed α-sheet peptides disrupt uropathogenic E. coli biofilms rendering bacteria susceptible to antibiotics and immune cells
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The cytoplasmic N-terminal tail of Zika virus NS4A protein forms oligomers in the absence of detergent or lipids
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Pixel-by-pixel autofluorescence corrected FRET in fluorescence microscopy improves accuracy for samples with spatially varied autofluorescence to signal ratio
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Food protein-derived amyloids do not accelerate amyloid β aggregation
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Regulatory mechanisms of the dynein-2 motility by post-translational modification revealed by MD simulation
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Sparse inference and active learning of stochastic differential equations from data
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The release of osteoclast-stimulating factors on supraphysiological loading by osteoprogenitors coincides with expression of genes associated with inflammation and cytoskeletal arrangement
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Urinalysis of individuals with renal hyperfiltration using ATR-FTIR spectroscopy
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Investigation of the motion of fullerene-wheeled nano-machines on thermally activated curved gold substrates
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Mapping periplasmic binding protein oligosaccharide recognition with neutron crystallography
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De novo Y1460C missense variant in NaV1.1 impedes the pore region and results in epileptic encephalopathy
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Epidermal growth factor receptor cascade prioritizes the maximization of signal transduction
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Retrospective study for the universal applicability of the residue-based linear free energy relationship in the two-state exchange of protein molecules
- Daisuke Fujinami
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Capacity and kinetics of light-induced cytochrome oxidation in intact cells of photosynthetic bacteria
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Biophysical and pharmacokinetic characterization of a small-molecule inhibitor of RUNX1/ETO tetramerization with anti-leukemic effects
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Spatial organization of hydrophobic and charged residues affects protein thermal stability and binding affinity
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Cellular mechanisms underlying state-dependent neural inhibition with magnetic stimulation
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SOD1 gains pro-oxidant activity upon aberrant oligomerization: change in enzymatic activity by intramolecular disulfide bond cleavage
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Structural and biochemical analysis reveals how ferulic acid improves catalytic efficiency of Humicola grisea xylanase
- Izadora Cristina Moreira Oliveira
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A comparative study of unpasteurized and pasteurized frozen whole hen eggs using size-exclusion chromatography and small-angle X-ray scattering
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Curvature dependence of BAR protein membrane association and dissociation kinetics
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Mechanisms of enhanced aggregation and fibril formation of Parkinson’s disease-related variants of α-synuclein
- Takashi Ohgita
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Improved fluorescent phytochromes for in situ imaging
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Investigating binding dynamics of trans resveratrol to HSA for an efficient displacement of aflatoxin B1 using spectroscopy and molecular simulation
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Structure of Escherichia coli O157:H7 bacteriophage CBA120 tailspike protein 4 baseplate anchor and tailspike assembly domains (TSP4-N)
- Kinlin L. Chao
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Modelling of the dynamic polarizability of macromolecules for single-molecule optical biosensing
- Larnii S. Booth
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- & Warwick P. Bowen
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The effects of molecular crowding and CpG hypermethylation on DNA G-quadruplexes formed by the C9orf72 nucleotide repeat expansion
- Kadir. A. Ozcan
- , Layla T. Ghaffari
- & Aaron R. Haeusler
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A computer-aided method for controlling chemical resistance of drugs using RRKM theory in the liquid phase
- Hamed Douroudgari
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An aberrant fused in sarcoma liquid droplet of amyotrophic lateral sclerosis pathological variant, R495X, accelerates liquid–solid phase transition