Research Highlights |
Featured
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Article |
Gold rotor bead tracking for high-speed measurements of DNA twist, torque and extension
Single-molecule structural transitions involving DNA twisting can be measured with substantially greater spatiotemporal resolution than previously possible with a gold rotor bead tracking (AuRBT) method. This approach uses magnetic tweezers and evanescent darkfield microscopy to track a gold nanoparticle probe attached to a DNA molecule.
- Paul Lebel
- , Aakash Basu
- & Zev Bryant
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News & Views |
Magnetic sequencing
Single-molecule DNA sequencing takes an important step in a surprising new direction with a sequence-detection method based on magnetic tweezers.
- Sten Linnarsson
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News in Brief |
Freely orbiting magnetic tweezers
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Brief Communication |
Magnetic torque tweezers: measuring torsional stiffness in DNA and RecA-DNA filaments
Magnetic torque tweezers are used to directly measure the torsional stiffness of single molecules of bare DNA and RecA filaments.
- Jan Lipfert
- , Jacob W J Kerssemakers
- & Nynke H Dekker