Research Briefing |
Featured
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Research Highlight |
Identifying the chromatin-associated proteome
ChromID identifies proteins associated with various chromatin modifications.
- Arunima Singh
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Research Highlights |
Learning the histone language
Sequential rounds of immunoprecipitation and barcoding reveal the genome-wide occurrence of paired histone marks.
- Nicole Rusk
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Methods in Brief |
Capturing lysine PTM–dependent interactions
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Article |
Genetic code expansion in stable cell lines enables encoded chromatin modification
Stable integration of genes that facilitate the incorporation of unnatural amino acids into the amber stop codon in genes of interest allows targeted integration of acetyl-lysine into histone H3.3 and the investigation of its effects in mouse embryonic stem cells.
- Simon J Elsässer
- , Russell J Ernst
- & Jason W Chin
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Methods in Brief |
Epigenome editing
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Research Highlights |
Tinkering with chromatin
Protein trans-splicing is used to study chromatin signaling in the cell nucleus.
- Allison Doerr
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Brief Communication |
Recombinant antibodies to histone post-translational modifications
Renewable affinity reagents with high specificity and affinity for histone modifications perform well in ChIP-seq and other applications in epigenetics research.
- Takamitsu Hattori
- , Joseph M Taft
- & Shohei Koide
Multifactorial epigenomic profiling of six chromatin states in single cells