Headache

Headache refers to pain of varying aetiology that is localized in the head and neck region. Most common reasons for primary headache are tension headache, migraine and neuropathic pain, such as trigeminal neuralgia. In secondary headache, the pain is a symptom of an underlying disorder.

Latest Research and Reviews

  • Research
    | Open Access

    The association between blood pressure (BP) and migraine is poorly understood. Here, the authors explore this relationship using summary-level GWAS data for BP and migraine. Cross-trait meta-analysis reveals shared loci between BP and migraine, while Mendelian randomization suggests that diastolic BP specifically plays a key role in migraine susceptibility.

    • Yanjun Guo
    • , Pamela M. Rist
    • , Iyas Daghlas
    • , Franco Giulianini
    • , Padhraig Gormley
    • , Verneri Anttila
    • , Bendik S. Winsvold
    • , Priit Palta
    • , Tonu Esko
    • , Tune H. Pers
    • , Kai-How Farh
    • , Ester Cuenca-Leon
    • , Mikko Muona
    • , Nicholas A. Furlotte
    • , Tobias Kurth
    • , Andres Ingason
    • , George McMahon
    • , Lannie Ligthart
    • , Gisela M. Terwindt
    • , Mikko Kallela
    • , Tobias M. Freilinger
    • , Caroline Ran
    • , Scott G. Gordon
    • , Anine H. Stam
    • , Stacy Steinberg
    • , Guntram Borck
    • , Markku Koiranen
    • , Lydia Quaye
    • , Hieab H. H. Adams
    • , Terho Lehtimäki
    • , Antti-Pekka Sarin
    • , Juho Wedenoja
    • , David A. Hinds
    • , Julie E. Buring
    • , Markus Schürks
    • , Paul M. Ridker
    • , Maria Gudlaug Hrafnsdottir
    • , Hreinn Stefansson
    • , Susan M. Ring
    • , Jouke-Jan Hottenga
    • , Brenda W. J. H. Penninx
    • , Markus Färkkilä
    • , Ville Artto
    • , Mari Kaunisto
    • , Salli Vepsäläinen
    • , Rainer Malik
    • , Andrew C. Heath
    • , Pamela A. F. Madden
    • , Nicholas G. Martin
    • , Grant W. Montgomery
    • , Mitja Kurki
    • , Mart Kals
    • , Reedik Mägi
    • , Kalle Pärn
    • , Eija Hämäläinen
    • , Hailiang Huang
    • , Andrea E. Byrnes
    • , Lude Franke
    • , Jie Huang
    • , Evie Stergiakouli
    • , Phil H. Lee
    • , Cynthia Sandor
    • , Caleb Webber
    • , Zameel Cader
    • , Bertram Muller-Myhsok
    • , Stefan Schreiber
    • , Thomas Meitinger
    • , Johan G. Eriksson
    • , Veikko Salomaa
    • , Kauko Heikkilä
    • , Elizabeth Loehrer
    • , Andre G. Uitterlinden
    • , Albert Hofman
    • , Cornelia M. van Duijn
    • , Lynn Cherkas
    • , Linda M. Pedersen
    • , Audun Stubhaug
    • , Christopher S. Nielsen
    • , Minna Männikkö
    • , Evelin Mihailov
    • , Lili Milani
    • , Hartmut Göbel
    • , Ann-Louise Esserlind
    • , Anne Francke Christensen
    • , Thomas Folkmann Hansen
    • , Thomas Werge
    • , Jaakko Kaprio
    • , Arpo J. Aromaa
    • , Olli Raitakari
    • , M. Arfan Ikram
    • , Tim Spector
    • , Marjo-Riitta Järvelin
    • , Andres Metspalu
    • , Christian Kubisch
    • , David P. Strachan
    • , Michel D. Ferrari
    • , Andrea C. Belin
    • , Martin Dichgans
    • , Maija Wessman
    • , Arn M. J. M. van den Maagdenberg
    • , John-Anker Zwart
    • , Dorret I. Boomsma
    • , George Davey Smith
    • , Kari Stefansson
    • , Nicholas Eriksson
    • , Mark J. Daly
    • , Benjamin M. Neale
    • , Jes Olesen
    • , Daniel I. Chasman
    • , Dale R. Nyholt
    • , Aarno Palotie
    • , Michelle Agee
    • , Adam Auton
    • , Robert K. Bell
    • , Katarzyna Bryc
    • , Sarah L. Elson
    • , Pierre Fontanillas
    • , Nicholas A. Furlotte
    • , David A. Hinds
    • , Karen E. Huber
    • , Aaron Kleinman
    • , Nadia K. Litterman
    • , Jennifer C. McCreight
    • , Matthew H. McIntyre
    • , Joanna L. Mountain
    • , Elizabeth S. Noblin
    • , Carrie A. M. Northover
    • , Steven J. Pitts
    • , J. Fah Sathirapongsasuti
    • , Olga V. Sazonova
    • , Janie F. Shelton
    • , Suyash Shringarpure
    • , Chao Tian
    • , Joyce Y. Tung
    • , Vladimir Vacic
    • , Tobias Kurth
    •  & Daniel I. Chasman

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