Genetics research

Genetics research is the scientific discipline concerned with the study of the role of genes in traits such as the development of disease. It has a key role in identifying potential targets for therapeutic intervention and also in understanding genetically based variations in response to therapeutic interventions.

Latest Research and Reviews

News and Comment

  • Comments and Opinion |

    Despite opprobrium from the scientific community, the creation of the first CRISPR babies by germline genome editing has led to a debate more about execution than intent. We need public education, engagement and empowerment to reach ‘broad societal consensus’ on whether, not how, to pursue heritable genome editing, argues Françoise Baylis.

    • Françoise Baylis
  • Research Highlights |

    A machine learning model predicts the genotype of CRISPR–Cas9 gene editing products, thereby enabling precise, template-free correction of disease-associated mutations.

    • Rita Strack
  • Comments and Opinion |

    • David K. Stevenson
    • , Ronald J. Wong
    • , Nima Aghaeepour
    • , Martin S. Angst
    • , Gary L. Darmstadt
    • , Daniel B. DiGiulio
    • , Maurice L. Druzin
    • , Brice Gaudilliere
    • , Ronald S. Gibbs
    • , Jeffrey B. Gould
    • , Michael Katz
    • , Jingjing Li
    • , Mira N. Moufarrej
    • , Cecele C. Quaintance
    • , Stephen R. Quake
    • , David A. Relman
    • , Gary M. Shaw
    • , Michael P. Snyder
    • , Xiaobin Wang
    •  & Paul H. Wise
  • Correspondence |

    • Weiyin Zhou
    • , Mitchell J. Machiela
    • , Neal D. Freedman
    • , Nathaniel Rothman
    • , Nuria Malats
    • , Casey Dagnall
    • , Neil Caporaso
    • , Lauren T. Teras
    • , Mia M. Gaudet
    • , Susan M. Gapstur
    • , Victoria L. Stevens
    • , Kevin B. Jacobs
    • , Joshua Sampson
    • , Demetrius Albanes
    • , Stephanie Weinstein
    • , Jarmo Virtamo
    • , Sonja Berndt
    • , Robert N. Hoover
    • , Amanda Black
    • , Debra Silverman
    • , Jonine Figueroa
    • , Montserrat Garcia-Closas
    • , Francisco X. Real
    • , Julie Earl
    • , Gaelle Marenne
    • , Benjamin Rodriguez-Santiago
    • , Margaret Karagas
    • , Alison Johnson
    • , Molly Schwenn
    • , Xifeng Wu
    • , Jian Gu
    • , Yuanqing Ye
    • , Amy Hutchinson
    • , Margaret Tucker
    • , Luis A. Perez-Jurado
    • , Michael Dean
    • , Meredith Yeager
    •  & Stephen J. Chanock
    Nature Genetics 51, 7-9