Genetic translocation articles within Nature

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• Article | 07 February 2012

  DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes

  A genome-wide analysis determines the contribution of DNA breaks and nuclear interactions to the formation of random versus recurrent translocations; whereas random translocations follow nuclear interaction profiles, the frequency of recurrent translocations is directly proportional to the amount of DNA damage at translocation partners.

  • Ofir Hakim
  • , Wolfgang Resch
  •  & Rafael Casellas

• Letter | 02 October 2011

  Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

  • Mark A. Dawson
  • , Rab K. Prinjha
  •  & Tony Kouzarides