Featured
-
-
Article
| Open Access
Regulation of TRI5 expression and deoxynivalenol biosynthesis by a long non-coding RNA in Fusarium graminearum
The fungus Fusarium graminearum produces a toxin, deoxynivalenol (DON), that can be found in cereal grains and processed food or feed. Here, Huang et al. study the regulation of DON biosynthesis and show that transcription factors TRI6 and TRI10 regulate each other’s expression and that of a long non-coding RNA which, in turn, downregulates a DON biosynthesis gene.
- Panpan Huang
- , Xiao Yu
- & Cong Jiang
-
Article
| Open Access
Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans
The transcription factor Hsf1 and the molecular chaperone Hsp90 modulate the heat shock response in the pathogen Candida albicans. Here, Leach et al. reveal a complex interplay between the two factors that regulates the expression of genes involved in the heat shock response and virulence.
- Michelle D. Leach
- , Rhys A. Farrer
- & Leah E. Cowen
-
Article
| Open Access
High genome heterozygosity and endemic genetic recombination in the wheat stripe rust fungus
Stripe rust is one of the most destructive wheat diseases. Here, Zheng and colleagues report a draft genome sequence of wheat stripe rust fungus, generated using a fosmid-to-fosmid approach, and provide insight into its race evolution and pathogenesis.
- Wenming Zheng
- , Lili Huang
- & Zhensheng Kang
Quantitative pathogenicity and host adaptation in a fungal plant pathogen revealed by whole-genome sequencing