DNA-binding proteins are proteins that bind to single- or double-stranded DNA, generally in the major groove if the binding is sequence-specific – as with transcription factors that regulate expression of genes, and nucleases that cleave DNA between nucleotides. DNA-binding proteins can also bind DNA non-specifically, such as polymerases and histones.
Latest Research and Reviews
Research | | openScientific Reports 7, 602
News and Comment
Research Highlights |Nature Methods 12, 809
Research Highlights |Nature Reviews Genetics 16, 317
Research Highlights |Nature Reviews Genetics 16, 258–259