Cytotoxic T cells

Definition

Cytotoxic T cells are CD8-postive T cells that are specialized for the direct killing of cells that are infected (particularly with viruses), cancerous or damaged in other ways. They express the glycoprotein CD8, as well as T cell receptors that recognize antigenic peptides presented by MHC class I molecules. There are two effector phenotypes: TC1 and TC2.

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