Combinatorial libraries articles within Scientific Reports

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• Article
  09 June 2020 | Open Access

  Catalyst-Free One-Pot Synthesis of Densely Substituted Pyrazole-Pyrazines as Anti-Colorectal Cancer Agents

  • Jia Xu
  • , Hong-Bo Tan
  •  & Zhi-Gang Xu

• Article
  27 February 2020 | Open Access

  Click Inspired Synthesis of Novel Cinchonidine Glycoconjugates as Promising Plasmepsin Inhibitors

  • Nidhi Mishra
  • , Anand K. Agrahari
  •  & Vinod K. Tiwari

• Article
  28 November 2019 | Open Access

  Specificity and Efficiency of the Uracil DNA Glycosylase-Mediated Strand Cleavage Surveyed on Large Sequence Libraries

  • Kathrin Hölz
  • , Angelina Pavlic
  •  & Mark M. Somoza

• Article
  15 August 2019 | Open Access

  Design of high-order antibiotic combinations against M. tuberculosis by ranking and exclusion

  • Kaan Yilancioglu
  •  & Murat Cokol

• Article
  17 July 2019 | Open Access

  Rapid Discovery and Structure-Property Relationships of Metal-Ion Fluorescent Sensors via Macroarray Synthesis

  • Apiwat Promchat
  • , Kanet Wongravee
  •  & Thanit Praneenararat

• Article
  30 October 2018 | Open Access

  Determination of extended substrate specificity of the MALT1 as a strategy for the design of potent substrates and activity-based probes

  • Paulina Kasperkiewicz
  • , Sonia Kołt
  •  & Marcin Drąg

• Article
  30 May 2018 | Open Access

  Palladium-Catalyzed Synthesis of Aldehydes from Aryl Iodides and Formic acid with Propylphosphonic Anhydride as the Activator

  • Xiao-Feng Wu

• Article
  01 February 2018 | Open Access

  Kaempferol mitigates Endoplasmic Reticulum Stress Induced Cell Death by targeting caspase 3/7

  • Ahmad Abdullah
  •  & Palaniyandi Ravanan

• Article
  19 January 2018 | Open Access

  Compositional Bias in Naïve and Chemically-modified Phage-Displayed Libraries uncovered by Paired-end Deep Sequencing

  • Bifang He
  • , Katrina F. Tjhung
  •  & Ratmir Derda

• Article
  19 December 2017 | Open Access

  Peptide Sequencing Directly on Solid Surfaces Using MALDI Mass Spectrometry

  • Zhan-Gong Zhao
  • , Lalaine Anne Cordovez
  •  & Neal Woodbury

• Article
  07 December 2017 | Open Access

  Protein-Structure Assisted Optimization of 4,5-Dihydroxypyrimidine-6-Carboxamide Inhibitors of Influenza Virus Endonuclease

  • Diane Beylkin
  • , Gyanendra Kumar
  •  & Thomas R. Webb

• Article
  20 November 2017 | Open Access

  Yeast display biopanning identifies human antibodies targeting glioblastoma stem-like cells

  • Michael Zorniak
  • , Paul A. Clark
  •  & John S. Kuo

• Article
  29 September 2017 | Open Access

  Regioselectivity and diastereoselectivity of three-component reaction of α-amino acid, dialkyl acetylenedicarboxylates and 2-arylidene-1,3-indanediones

  • Liang Chen
  • , Jing Sun
  •  & Chao-Guo Yan

• Article
  21 September 2017 | Open Access

  Stepwise Evolution Improves Identification of Diverse Peptides Binding to a Protein Target

  • Victor I. Lyamichev
  • , Lauren E. Goodrich
  •  & Jigar J. Patel

• Article
  20 July 2017 | Open Access

  Structure-Based Discovery of Small Molecule Inhibitors of Cariogenic Virulence

  • Qiong Zhang
  • , Bhavitavya Nijampatnam
  •  & Hui Wu

• Article
  25 May 2016 | Open Access

  Identification of Leishmania donovani Topoisomerase 1 inhibitors via intuitive scaffold hopping and bioisosteric modification of known Top 1 inhibitors

  • Rajinikanth Mamidala
  • , Papiya Majumdar
  •  & Subhabrata Sen

• Article
  09 March 2016 | Open Access

  PEGylated substrates of NSP4 protease: A tool to study protease specificity

  • Magdalena Wysocka
  • , Natalia Gruba
  •  & Adam Lesner

• Article
  08 March 2016 | Open Access

  A “building block” approach to the new influenza A virus entry inhibitors with reduced cellular toxicities

  • Dongguo Lin
  • , Fangfang Li
  •  & Jian He

• Article
  07 October 2015 | Open Access

  Design, Synthesis and Structure-Activity Relationship Optimization of Lycorine Derivatives for HCV Inhibition

  • Duozhi Chen
  • , Jieyun Cai
  •  & Xiaojiang Hao

• Article
  25 September 2015 | Open Access

  High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations

  • Bryan T. Mott
  • , Richard T. Eastman
  •  & Craig J. Thomas

• Article
  23 July 2015 | Open Access

  Predominant structural configuration of natural antibody repertoires enables potent antibody responses against protein antigens

  • Hong-Sen Chen
  • , Shin-Chen Hou
  •  & An-Suei Yang

• Article
  20 July 2015 | Open Access

  Economical analysis of saturation mutagenesis experiments

  • Carlos G. Acevedo-Rocha
  • , Manfred T. Reetz
  •  & Yuval Nov

• Article
  10 June 2015 | Open Access

  Encoded Library Synthesis Using Chemical Ligation and the Discovery of sEH Inhibitors from a 334-Million Member Library

  • Alexander Litovchick
  • , Christoph E. Dumelin
  •  & Matthew A. Clark

• Article
  28 January 2015 | Open Access

  A transcription blocker isolated from a designed repeat protein combinatorial library by in vivo functional screen

  • Elena B. Tikhonova
  • , Abdul S. Ethayathulla
  •  & Lan Guan

• Article
  19 September 2014 | Open Access

  Serum Stable Natural Peptides Designed by mRNA Display

  • Shannon M. Howell
  • , Stephen V. Fiacco
  •  & Richard W. Roberts