Featured
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News Feature |
Cancer research: Open ambition
Jay Bradner believes that cancer can be defeated through control of epigenetics — and he is not shy about spreading the word.
- Amy Maxmen
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Feature |
Epigenetics: Marked for success
The growing field of cancer epigenetics demands computational expertise and translational research experience. Qualified practitioners are in high demand.
- Heidi Ledford
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Article
| Open Access
A novel retinoblastoma therapy from genomic and epigenetic analyses
The retinoblastoma genome is shown to be stable, but multiple cancer pathways are identified that are epigenetically deregulated, providing potential new therapeutic targets.
- Jinghui Zhang
- , Claudia A. Benavente
- & Michael A. Dyer
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Letter |
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
- Johannes Zuber
- , Junwei Shi
- & Christopher R. Vakoc
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Perspective |
Epigenetics as a unifying principle in the aetiology of complex traits and diseases
- Arturas Petronis
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Editorial |
Time for the epigenome
The complexity of genetic regulation is one of the great wonders of nature, but it represents a daunting challenge to unravel. The International Human Epigenome Consortium is an appropriate response.
Genome-wide detection of DNase I hypersensitive sites in single cells and FFPE tissue samples