Cellular immunity articles within Nature Reviews Nephrology

Featured

• Review Article | 25 February 2019

  Immune mechanisms of salt-sensitive hypertension and renal end-organ damage

  Immune mechanisms have important roles in the development of hypertension and end-organ damage. In this Review, David Mattson discusses these mechanisms with a focus on salt-sensitive hypertension and adaptive immunity.

  • David L. Mattson

• Review Article | 29 February 2016

  Memory T cells in organ transplantation: progress and challenges

  Memory T cells and their ability to generate an anamnestic response are vital for protective immunity, but have a potentially detrimental impact on allograft survival. Here, Allan Kirk and colleagues discuss the generation of memory T cells, their role in allograft rejection and therapeutic strategies that target allospecific memory T-cell responses and might improve outcomes in organ transplantation.

  • Jaclyn R. Espinosa
  • , Kannan P. Samy
  •  & Allan D. Kirk