Cancer models articles within Nature

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  • Letter |

    The hilum (a transitional region) of the mouse ovary is identified as a stem cell niche of the ovarian surface epithelium, and its cells are prone to malignant transformation after inactivation of common tumour suppressor genes, suggesting that they may be the origin of ovarian carcinoma.

    • Andrea Flesken-Nikitin
    • , Chang-Il Hwang
    •  & Alexander Yu. Nikitin
  • News & Views |

    Large panels of human cancer cell lines, profiled at the DNA, RNA and chromosomal levels and tested for sensitivity to approved and potential drugs, will accelerate the search for new cancer therapies. See Article p.570 & Letter p.603

    • John N. Weinstein