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Heterogeneous silicon mesostructures for lipid-supported bioelectric interfaces
A biocompatible and biodegradable mesostructured form of silicon is used to make lipid-bilayer-supported bioelectric interfaces that can optically modulate the electrophysiology of single dorsal root ganglia neurons.
- Yuanwen Jiang
- , João L. Carvalho-de-Souza
- & Bozhi Tian
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Three-dimensional macroporous nanoelectronic networks as minimally invasive brain probes
An ultra-flexible cylindrical mesh embedding multiple electrodes bending away from the device is used to probe rodents’ neural activity in vivo. This geometry improves the neuron–probe contact and reduces tissue response in chronic applications.
- Chong Xie
- , Jia Liu
- & Charles M. Lieber
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Macroporous nanowire nanoelectronic scaffolds for synthetic tissues
Three-dimensional bioactive scaffolds can support tissue growth for studies in cellular biophysics and regenerative medicine. Such scaffolds have now been integrated with semiconductor nanowires to probe their porous interior, allowing for real-time monitoring of signals such as the response of neural and cardiac tissue models to drugs.
- Bozhi Tian
- , Jia Liu
- & Charles M. Lieber