Review Article
|
Open Access
Featured
-
-
Review Article
| Open AccessSkin-interfacing wearable biosensors for smart health monitoring of infants and neonates
Wearable sensors have been widely studied, but research has tended to focus on their use in adults. This Review explores skin-interfacing smart health systems that are designed with infants and neonates in mind.
- Lauren Zhou
- , Matthew Guess
- & Woon-Hong Yeo
-
Article
| Open Access3D printed titanium carbide MXene-coated polycaprolactone scaffolds for guided neuronal growth and photothermal stimulation
Neural circuitry is important for comprehending computational mechanisms and physiology of the brain but controlling neuronal connectivity and response in 3D is challenging. Here, titanium carbide MXene-coated 3D polycaprolactone scaffolds are demonstrated to effectively control neuronal interconnection.
- Jianfeng Li
- , Payam Hashemi
- & Joyce K. S. Poon
-
Perspective
| Open AccessTowards a digitally connected body for holistic and continuous health insight
Wearable electronics provide opportunities for personalized health monitoring and treatment. This Perspective addresses challenges in the field, including material selection for devices, device integration strategies, and public adoption factors.
- Philipp Gutruf
-
Review Article
| Open AccessEngineering receptor-mediated transmembrane signaling in artificial and living cells
Transmembrane signaling systems are present in living cells which receive cues from the environment and produce a cellular response. Here, recent advances in the design of bioinspired systems that mimic transmembrane signaling in synthetic and living cells are reviewed.
- Ke Shi
- , Chuwen Song
- & Yiyang Lin
-
Article
| Open AccessEffect of grip-enhancing agents on sliding friction between a fingertip and a baseball
Foreign substances on the surface of a baseball can alter its delivery and enhance pitching performance. Here, sticky substances are found to increase finger-ball friction which can positively affect spin rate, whereas rosin powder can ensure consistent friction across pitchers, with results differing between baseballs used in the United States and Japan.
- Takeshi Yamaguchi
- , Daiki Nasu
- & Kei Masani
-
Article
| Open AccessUnraveling the effect of collagen damage on bone fracture using in situ synchrotron microtomography with deep learning
Collagen is known to play a key role in the fracture resistance of bone. Here, in situ synchrotron tomography during the mechanical testing of bone is combined with deep learning to mitigate radiation damage, revealing that a compromised collagen network lowers the efficacy of crack deflection.
- Michael Sieverts
- , Yoshihiro Obata
- & Claire Acevedo
-
Article
| Open AccessIn vivo engraftment into the cornea endothelium using extracellular matrix shrink-wrapped cells
Tissue regeneration by injecting cells into the damaged area is a common clinical treatment, but is not always affective. Here, a shrink-wrap-like process is reported for corneal endothelial cells, allowing them to be engrafted into the corneal endothelium of a rabbit animal model.
- Rachelle N. Palchesko
- , Yiqin Du
- & Adam W. Feinberg
-
Perspective
| Open AccessOrganic semiconductors for light-mediated neuromodulation
There is growing interest in organic semiconductor devices for light-mediated neuromodulation, such as for retinal stimulation. Here, the key working principles of these devices are discussed, as well as promising applications and outstanding challenges for the field.
- Danashi Imani Medagoda
- & Diego Ghezzi
-
Review Article
| Open AccessDesign principles and biological applications of red-emissive two-photon carbon dots
Carbon dots are suitable for a range of biological applications due to their unique physicochemical properties and biological behavior. This Review summarizes research related to the emerging field of red-emissive two-photon carbon dots for bioimaging, biosensing, and phototherapeutic applications.
- Pooria Lesani
- , Aina Hazeera Mohamad Hadi
- & Hala Zreiqat
-
Article
| Open AccessMicrostructure analysis and image-based modelling of face masks for COVID-19 virus protection
Face masks are key for slowing the spread of COVID-19. Here, the microstructure of three common masks is determined by x-ray tomography, combined with image-based modelling of droplet permeability, revealing that N95 masks are best for droplet filtration.
- Wenjia Du
- , Francesco Iacoviello
- & Paul R. Shearing
-
Article
| Open Access4D printing of reconfigurable metamaterials and devices
Shape-shifting structures are important building blocks in the design of reconfigurable materials and devices with advanced functionalities. Here, versatile metamaterials with 3D-to-3D shape-shifting behavior upon thermal activation are fabricated by adapting a 3D printer to print on curved surfaces.
- Teunis van Manen
- , Shahram Janbaz
- & Amir A. Zadpoor
-
Article
| Open AccessPhotovoltaic retinal prosthesis restores high-resolution responses to single-pixel stimulation in blind retinas
A major challenge artificial retinas face is being able to activate neurons across a wide visual field. Here, a photovoltaic epiretinal prosthetic with over 10,000 pixels shows wide retinal coverage and single-pixel illumination, offering high spatial resolution discrimination in mouse models.
- Naïg Aurelia Ludmilla Chenais
- , Marta Jole Ildelfonsa Airaghi Leccardi
- & Diego Ghezzi
-
Article
| Open AccessPhotovoltaic neurointerface based on aluminum antimonide nanocrystals
Artificial retinas require materials and devices that can interface with the nervous system. Here, aluminum antimonide colloidal nanocrystals are used as the interfacing layer with a biological medium, showing a fast photoresponse of 55 µs and a suggested operational lifetime of 36 months.
- Mertcan Han
- , Houman Bahmani Jalali
- & Sedat Nizamoglu
-
Article
| Open AccessThe role of valve stiffness in the insurgence of deep vein thrombosis
Deep vein thrombosis is the clotting of blood in deep veins. Here, a microfluidic device containing flexible valves fabricated in-situ is used to investigate the effects of blood flow conditions and valve elasticity on thrombus formation, revealing the circumstance under which clotting occurs.
- Zoe Schofield
- , Hosam Alden Baksamawi
- & Daniele Vigolo
-
Article
| Open AccessPhotovoltaic organic interface for neuronal stimulation in the near-infrared
Organic materials are attractive for photovoltaic interfaces in bioelectronics, but are limited by adhesion in aqueous environments and responsiveness in the visible spectrum. Here, an organic interface is reported for neuronal stimulation in the near-infrared and tested on explanted mice retinas.
- Marta Jole Ildelfonsa Airaghi Leccardi
- , Naïg Aurelia Ludmilla Chenais
- & Diego Ghezzi
-
Article
| Open AccessSimulating nephron ion transport function using activated wafer electrodeionization
The nephrons in the kidney transport ions and organic molecules, but may not work effectively in patients with kidney disease. Here, a synthetic nephron is created, based on activated wafer electrodeionization, and shown to enable the transport of several physiologically relevant ions.
- Christa N. Hestekin
- , Jamie A. Hestekin
- & Ira Kurtz