Behavioural genetics

Behavioural genetics is the interdisciplinary effort to establish causal links between genes and animal (including human) behavioural traits and neural mechanisms. Methods used include twin studies, quantitative trait mapping by linkage to allelic variants, transgenic animals and targeted gene disruption or silencing.

Latest Research and Reviews

News and Comment

  • Research Highlights |

    A study in Nature Genetics reports the first genome-wide significant loci for attention deficit/hyperactivity disorder and implicates biologically informative genes, such as FOXP2, as contributors to its aetiology.

    • Dorothy Clyde
  • Comments and Opinion |

    Inbred mice are preferred over outbred mice because it is assumed that they display less trait variability. We compared coefficients of variation and did not find evidence of greater trait stability in inbred mice. We conclude that contrary to conventional wisdom, outbred mice might be better subjects for most biomedical research.

    • Alexander H. Tuttle
    • , Vivek M. Philip
    • , Elissa J. Chesler
    •  & Jeffrey S. Mogil
    Nature Methods 15, 994-996
  • Research Highlights |

    One in four UK adults over the age of 65 suffers from loneliness. An analysis of UK Biobank data has identified 15 genomic loci associated with loneliness and reports a possible causal link between obesity and loneliness and depression.

    • Dorothy Clyde