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Turning Dicer on its head

Nature Structural & Molecular Biology volume 19, pages 365–366 (2012)Cite this article

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Abstract

Recent structural analysis of full-length human Dicer supports a new model of the enzyme's domain arrangement and provides a structural basis for many of Dicer's biochemical attributes.

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Figure 1: Human Dicer domain architecture.

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Authors and Affiliations

  1. Ahilya N. Sawh and Thomas F. Duchaine are in the Goodman Cancer Research Centre and in the Department of Biochemistry, McGill University, Montreal, Quebec, Canada.,

    Ahilya N Sawh & Thomas F Duchaine

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  1. Ahilya N Sawh
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  2. Thomas F Duchaine
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Correspondence to Thomas F Duchaine.

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The authors declare no competing financial interests.

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Sawh, A., Duchaine, T. Turning Dicer on its head. Nat Struct Mol Biol 19, 365–366 (2012). https://doi.org/10.1038/nsmb.2275

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