Nature Structural & Molecular Biology
12, 832 - 833 (2005)
doi:10.1038/nsmb1005-832
Taking control of G-quadruplexesPeter Baumann
The author is at the Stowers Institute for Medical Research, 1000 E. 50th Street, Kansas City, Missouri 64110, USA and the Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, 3901 Rainbow Boulevard, Kansas City, Kansas 66160, USA.
peb@stowers-institute.org
Telomeres are crucial for maintaining the integrity of the genome. Several alternative structures have been proposed for these caps, and understanding their biological significance is a matter of great interest. Probing of native telomeres now reveals that telomere end-binding proteins may control the formation of G-quadruplex DNA in vivo.
MORE ARTICLES LIKE THIS These links to content published by NPG are automatically generated.
|
