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Artificial neural networks (ANNs) have been developed for various applications in prostate cancer management, but their ability to perform in this setting remains controversial. In this Viewpoint, authors from the University Hospital Charité present the case for ANNs, and argue that urologists should be using these tools in clinical decision-making.
Diabetes mellitus is associated with a number of different vascular and neurologic problems that can lead to the development of bladder dysfunction, erectile dysfunction and retrograde ejaculation. This review by Domenico Fedele examines the mechanisms that lead to the development of these urologic problems in patients with diabetes, and discusses appropriate treatment and management options.
Hitherto-neglected investigation of processes that underlie the characteristic feature of Peyronie's disease—deposition of fibrotic plaques in the penile tunica albuginea—has been kick-started by the recent development of two rat models. This update of new data is framed around the hypothesis that Peyronie's plaques are a product of perturbed interplay between profibrotic and antifibrotic factors, induced by trauma.
