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Recommendations for children and adolescents with single kidneys (like most survivors of Wilms tumour) for taking part in contact sporting activities are not aligned worldwide. This discrepancy can create misunderstandings regarding the perceived and real risk of abdominal impact and trauma when practising some sports.
Trends in vasectomy use are controversial, but rates might be declining over time. Several factors could contribute to this apparent decrease, which warrant consideration before definitive conclusions are made.
Treatment for childhood cancer can cause infertility in patients who survive to adulthood. Jensen et al. discuss the options for fertility preservation in pre-pubertal and pubertal boys, covering preservation of spermatozoa and testis tissue, as well as psychological and ethical issues, and current challenges to fertility preservation.
A number of penile traction therapy and vacuum erection devices are available for the management of patients with erectile dysfunction, Peyronie’s disease, penile dysmorphophobia, before and after penile prosthesis insertion, and after radical prostatectomy. However, the optimal device for each indication differs and, for some indications, research is limited. In this Review, Sultana and colleagues present a variety of devices that are available and consider challenges such as compliance, cost and availability.
The prostate is divided into the peripheral, transition and central zones, which have different prostate cancer incidences and prognoses. Differences between the zones suggest their potential roles in tumour aggressiveness, but treatment of prostate cancer remains zonal agnostic. Improved understanding of the zones and their roles in tumorigenesis could improve prostate cancer management.
Early studies in patients and animal models have suggested that SARS-CoV-2 can access the reproductive system and could have effects on fertility. In this Perspective, Edenfield and Easley present the evidence for mechanisms of infection of reproductive cells by SARS-CoV-2 and consider the potential for testicular dysfunction in patients who have had COVID-19.
