Achieving the best possible practice in the management of patients with penile cancer is hampered by a lack of evidence owing to the rare occurrence of this disease. New population-based data from the USA show improved surgical and medical practice patterns but also highlight challenges in providing optimum care to all patients.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Mossanen, M., Holt, S., Gore, J. L., Lin, D. W. & Wright, J. L. 15 years of penile cancer management in the United States: an analysis of the use of partial penectomy for localized disease and chemotherapy in the metastatic setting. Urol. Oncol. http://dx.doi.org/10.1016/j.urolonc.2016.06.019 (2016).
Sri, D. et al. The significance of close surgical margins in organ sparing surgery for penile squamous cell cancer [abstract 4]. J. Clin. Urol. 9 (Suppl.), 10 (2016).
Osinibi, E. et al. Patient reported outcomes of glans resurfacing for penile lichen sclerosis and malignancy [abstract P99]. BJU Int. 115 (Suppl. 7), 56 (2015).
Nicholson, S. et al. Phase II trial of docetaxel, cisplatin and 5FU chemotherapy in locally advanced and metastatic penis cancer (CRUK/09/001). Br. J. Cancer 109, 2554–2559 (2013).
Djajadiningrat, R. S., Bergman, A. M., van Werkhoven, E., Vegt, E. & Horenblas, S. Neoadjuvant taxane-based combination chemotherapy in patients with advanced penile cancer. Clin. Genitourin. Cancer 13, 44–49 (2015).
Leijte, J. A. et al. Recurrence patterns of squamous cell carcinoma of the penis: recommendations for follow-up based on a two-centre analysis of 700 patients. Eur. Urol. 54, 161–168 (2008).
Hakenberg, O. W. et al. EAU guidelines on penile cancer: 2014 update. Eur. Urol. 67, 142–150 (2015).
Ayres, B. et al. Recent trends in incidence and mortality of penile cancer in England [abstract 1052]. Eur. Urol. Suppl. 6, 285 (2007).
Torbrand, C. et al. Socioeconomic factors and penile cancer risk and mortality; a population-based study. BJU Int. http://dx.doi.org/10.1111/bju.13534 (2016).
Nicholson, S., Kayes, O. & Minhas, S. Clinical trial strategy for penis cancer. BJU Int. 113, 852–853 (2014).
Author information
Authors and Affiliations
Contributions
B.A. researched data for the article and wrote the manuscript. Both authors made a substantial contribution to discussion of content and reviewed and/or edited the manuscript before submission.
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Ayres, B., Watkin, N. Welcome changes in disease management and remaining challenges. Nat Rev Urol 13, 637–639 (2016). https://doi.org/10.1038/nrurol.2016.204
Published:
Issue Date:
DOI: https://doi.org/10.1038/nrurol.2016.204
