Unequivocal randomized trial data show that PSA velocity does not benefit decision making in localized prostate cancer. A recent paper suggests that the literature is wrong and that PSA velocity does predict aggressive disease; however, the study design is flawed and the key claim seems to be based on a typographical error.
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Vickers, A. Why is PSA velocity such a sticky concept?. Nat Rev Urol 10, 189–190 (2013). https://doi.org/10.1038/nrurol.2013.47
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DOI: https://doi.org/10.1038/nrurol.2013.47